What questions should be asked when evaluating a patient with new onset knee pain?

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Last updated: August 7, 2025View editorial policy

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Key Questions for Evaluating New Onset Knee Pain

When evaluating a patient with new onset knee pain, ask targeted questions about pain characteristics, mechanism of injury, associated symptoms, and functional limitations to guide diagnosis and treatment decisions. 1

Pain Characteristics

  • Location of pain (anterior, posterior, medial, lateral, or diffuse)
  • Onset (sudden vs. gradual)
  • Duration (how long has the pain been present)
  • Quality (sharp, dull, aching, burning)
  • Severity (on a scale of 0-10)
  • Timing (constant vs. intermittent)
  • Aggravating factors (activities that worsen pain)
  • Relieving factors (what makes the pain better)

Mechanism of Injury

  • Was there a specific traumatic event?
  • Details of any fall or twisting injury
  • Position of the knee during injury
  • Force and direction of impact
  • Activity being performed when pain began
  • Any sound heard during injury (pop, snap, crack)

Associated Symptoms

  • Swelling (timing, amount, recurrence) 2
  • Mechanical symptoms:
    • Locking (inability to fully extend the knee)
    • Popping or clicking
    • Giving way or instability 2
  • Ability to bear weight immediately after injury
  • Changes in range of motion
  • Redness or warmth around the joint
  • Fever or systemic symptoms (suggesting infection)

Functional Assessment

  • Ability to bear weight currently
  • Impact on daily activities
  • Difficulty with stairs (ascending vs. descending)
  • Problems with walking, running, or standing
  • Changes in gait pattern
  • Use of assistive devices

Past Medical History

  • Previous knee injuries or surgeries
  • History of arthritis or other joint conditions
  • Recent illnesses or infections
  • Current medications
  • History of gout or pseudogout
  • Recent changes in activity level or exercise routine

Red Flags to Identify

  • Inability to bear weight 3
  • Gross deformity of the knee 3
  • Fever with joint pain (suggesting infection)
  • Severe pain unresponsive to rest and over-the-counter medications
  • Progressive worsening of symptoms despite conservative measures
  • Neurological symptoms (numbness, tingling)
  • History suggesting increased risk of fracture 3

Physical Examination Focus Points

  • Compare with the uninjured knee 4
  • Inspect for swelling, erythema, deformity
  • Palpate for point tenderness along joint lines 2
  • Assess range of motion (active and passive) 4
  • Evaluate ligament stability (collateral and cruciate) 4
  • Perform special tests based on suspected pathology:
    • McMurray's test for meniscal injuries
    • Lachman test for anterior cruciate ligament
    • Valgus/varus stress tests for collateral ligaments 4

Common Pitfalls to Avoid

  • Failing to obtain weight-bearing radiographs when evaluating for osteoarthritis 1
  • Neglecting to assess hip and spine as potential sources of referred knee pain 3
  • Overlooking the importance of weight management in overweight patients 1
  • Delaying appropriate imaging in cases of significant trauma 1
  • Not re-examining the knee after acute pain subsides (3-5 days post-injury) 1

By systematically addressing these questions, you can efficiently evaluate new onset knee pain and determine appropriate next steps for diagnosis and management.

References

Guideline

Knee Injury Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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