Differential Diagnosis for Minimal Bleeding from One Breast

• Single most likely diagnosis
  • Ductal Ectasia: This condition is characterized by the dilation of milk ducts, often causing minimal bleeding from one breast. It is a common and benign condition, especially in older women.
• Other Likely diagnoses
  • Intraductal Papilloma: A small, benign tumor that grows in the milk ducts of the breast, often causing bleeding from one breast. It is more common in women over 40.
  • Breast Trauma: Minor injury to the breast can cause bleeding, especially if it affects the ducts or small blood vessels.
  • Hormonal Changes: Fluctuations in hormone levels, such as those experienced during menstruation or menopause, can lead to breast changes, including minimal bleeding.
• Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
  • Breast Cancer: Although less common, breast cancer can present with bleeding from the nipple. It is crucial to rule out cancer, especially in women with risk factors or those over 40.
  • Paget's Disease of the Breast: A rare form of breast cancer that affects the skin of the nipple and, sometimes, the areola. It can cause bleeding, and early detection is vital.
• Rare diagnoses
  • Breast Infection or Abscess: An infection of the breast tissue can cause bleeding, although this is less common and usually accompanied by other symptoms like pain and swelling.
  • Endocrine Disorders: Certain endocrine conditions, such as hyperprolactinemia, can lead to galactorrhea (spontaneous milk production) and, occasionally, minimal bleeding.