Differential Diagnosis for 20 yo Female with Pulmonary Infiltrates, Lymphadenopathy, and Recurrent Fevers
- Single Most Likely Diagnosis
- Systemic Lupus Erythematosus (SLE): The presence of pulmonary infiltrates, lymphadenopathy, recurrent fevers, and a positive antinuclear antibody (ANA) test are all consistent with SLE, a chronic autoimmune disease that can affect multiple organ systems.
- Other Likely Diagnoses
- Sarcoidosis: This condition can cause pulmonary infiltrates, lymphadenopathy, and fever, and can also be associated with a positive ANA test in some cases.
- Rheumatoid Arthritis (RA): While RA is more commonly associated with joint symptoms, it can also cause pulmonary infiltrates, lymphadenopathy, and fever, and some patients with RA may have a positive ANA test.
- Mixed Connective Tissue Disease (MCTD): This condition overlaps with SLE, RA, and other autoimmune diseases, and can cause a variety of symptoms including pulmonary infiltrates, lymphadenopathy, and fever.
- Do Not Miss Diagnoses
- Lymphoma: This is a type of cancer that can cause lymphadenopathy, fever, and pulmonary infiltrates, and would be a critical diagnosis to miss.
- Tuberculosis (TB): While the patient has been treated for infection, TB can be difficult to diagnose and would be a critical diagnosis to miss, especially if the patient has been exposed to someone with TB or has traveled to an area where TB is common.
- Histoplasmosis: This is a fungal infection that can cause pulmonary infiltrates, lymphadenopathy, and fever, and would be a critical diagnosis to miss, especially if the patient has been exposed to bird or bat droppings.
- Rare Diagnoses
- Wegener's Granulomatosis: This is a rare autoimmune disease that can cause pulmonary infiltrates, lymphadenopathy, and fever, but is less likely than some of the other diagnoses on this list.
- Churg-Strauss Syndrome: This is another rare autoimmune disease that can cause pulmonary infiltrates, lymphadenopathy, and fever, but is less likely than some of the other diagnoses on this list.
- Eosinophilic Granuloma with Polyangiitis (EGPA): This is a rare condition that can cause pulmonary infiltrates, lymphadenopathy, and fever, but is less likely than some of the other diagnoses on this list.