Other Names for Versed (Midazolam)
Versed is the brand name for midazolam, a short-acting benzodiazepine used for sedation, anxiolysis, amnesia, and seizure control. 1
Generic and Brand Names
Midazolam is known by several names:
- Generic name: Midazolam
- Brand names:
- Versed (original brand name in the United States)
- Dormicum (common brand name in many countries outside the US)
- Hypnovel (brand name in some countries)
Pharmacological Classification
Midazolam belongs to the:
- Benzodiazepine class of medications
- Specifically, it's an imidazobenzodiazepine derivative 2
- First water-soluble benzodiazepine 3, 4
Unique Properties
Midazolam has distinctive characteristics that differentiate it from other benzodiazepines:
- Water-soluble at pH less than 4 (in the injectable formulation) 3
- Becomes lipid-soluble at physiological pH (above 4), allowing it to cross the blood-brain barrier quickly 3, 5
- Short-acting with rapid onset of action:
Clinical Applications
Midazolam is commonly used for:
- Procedural sedation in emergency departments 4
- Premedication before surgical procedures 2
- Treatment of seizures, including status epilepticus 6, 7
- Anxiolysis and amnesia 7
- Sedation in intensive care settings 2
- Induction agent for rapid sequence intubation 6, 7
Important Clinical Considerations
- Midazolam is approximately 2-4 times more potent than diazepam 4
- Respiratory depression is the primary safety concern, especially when combined with opioids 1, 7
- Flumazenil can be used as a reversal agent in emergency situations 6, 1
- Dose adjustments are required for elderly patients, and those with hepatic or renal impairment 1
Understanding that Versed is midazolam helps healthcare providers recognize this medication across different settings and documentation systems, ensuring safe and appropriate use.