What is the differential diagnosis of nocturnal diaphoresis (night sweats)?

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Differential Diagnosis for Night Sweats

Single Most Likely Diagnosis

  • Hypertension: Night sweats can be associated with hypertension, possibly due to the body's increased blood pressure and heart rate during sleep.
  • Menopause: Hot flashes and night sweats are common symptoms of menopause, caused by hormonal changes.
  • Anxiety or Stress: Stress and anxiety can cause night sweats due to the body's "fight or flight" response.

Other Likely Diagnoses

  • Infections: Tuberculosis, endocarditis, and osteomyelitis can cause night sweats due to the body's immune response.
  • Hormonal Imbalances: Hyperthyroidism, pheochromocytoma, and carcinoid syndrome can cause night sweats due to excessive hormone production.
  • Medications: Certain medications, such as antidepressants, can cause night sweats as a side effect.
  • Sleep Disorders: Sleep apnea, insomnia, and restless leg syndrome can cause night sweats due to disrupted sleep patterns.

Do Not Miss Diagnoses

  • Lymphoma: Night sweats can be a symptom of lymphoma, particularly Hodgkin's lymphoma.
  • Tuberculosis: Although less common in developed countries, tuberculosis is a serious infection that can cause night sweats.
  • Endocarditis: Infectious endocarditis is a life-threatening condition that can cause night sweats.
  • Pheochromocytoma: This rare tumor can cause excessive adrenaline production, leading to night sweats.

Rare Diagnoses

  • Brucellosis: A rare bacterial infection that can cause night sweats.
  • Histoplasmosis: A fungal infection that can cause night sweats, particularly in immunocompromised individuals.
  • Castleman Disease: A rare lymphoproliferative disorder that can cause night sweats.
  • Whipple's Disease: A rare bacterial infection that can cause night sweats, among other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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