What are the characteristics of hypertrophic pulmonary osteoarthropathy (HPOA) in the hands?

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Last updated: March 7, 2025View editorial policy

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From the Research

Hypertrophic pulmonary osteoarthropathy (HPOA) in the hands is characterized by digital clubbing, periosteal new bone formation, and synovitis, typically associated with underlying lung disease, and treatment primarily focuses on addressing the underlying pulmonary condition. The characteristics of HPOA in the hands include clubbing of fingers, periosteal new bone formation, and synovitis, as reported in a case study published in 2021 1. This condition is often associated with underlying lung disease, such as lung cancer, and can cause significant pain and discomfort.

Key Characteristics of HPOA

  • Digital clubbing
  • Periosteal new bone formation
  • Synovitis
  • Association with underlying lung disease, such as lung cancer

Treatment Options

Treatment for HPOA primarily focuses on addressing the underlying pulmonary condition, which can include tumor resection, chemotherapy, or other treatments for lung cancer.

  • Tumor resection is often the most effective treatment for HPOA associated with lung cancer 1.
  • Symptom management may include NSAIDs, such as ibuprofen or naproxen, to reduce pain and inflammation.
  • In more severe cases, bisphosphonates, such as pamidronate or zoledronic acid, may provide relief 2, 3. Regular follow-up is essential to monitor both symptom progression and the underlying pulmonary disease.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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