How to Get Adequate Vitamin D
The most effective way to ensure adequate vitamin D levels is through a combination of sensible sun exposure, dietary sources, and supplementation with 800 IU daily for most adults, increasing to 2,000 IU daily for high-risk individuals. 1
Sources of Vitamin D
Sun Exposure
- Vitamin D is naturally produced in the skin through UVB radiation exposure
- Humans are largely dependent on UVB-radiation-induced photosynthesis of vitamin D 2
- Sensible sun exposure is an inexpensive and enjoyable way to maintain vitamin D stores for those not at risk of deficiency 3
- However, excessive sun exposure should be avoided due to skin cancer risk
Dietary Sources
- Few foods naturally contain vitamin D, making it difficult to obtain adequate amounts from diet alone 2
- Natural food sources include:
- Fatty fish (salmon, mackerel)
- Egg yolks
- Fortified foods (milk, orange juice, cereals)
Supplementation
Supplementation is recommended for:
High-risk populations without baseline measurement 4, 1:
- Dark-skinned or veiled individuals: 800 IU/day
- Adults ≥65 years: 800 IU/day
- Institutionalized individuals: 800 IU/day
Other individuals after 25(OH)D measurement if levels <30 ng/mL 4, 1:
- Initial corrective dose: 50,000 IU weekly for 8 weeks
- Followed by maintenance dose: 800 IU/day
Optimal Dosing Recommendations
Daily Maintenance Dosing
- General adult population: 600-800 IU/day 1
- Adults over 70 years: 800 IU/day 1
- High-risk individuals: 800-2,000 IU/day 1, 5
Correcting Deficiency
- For documented vitamin D deficiency (<20 ng/mL):
- 50,000 IU weekly for 8 weeks 1
- Followed by appropriate maintenance dose
- Recheck levels after 3 months of supplementation
Dosing Considerations
- Rule of thumb: 1,000 IU daily increases 25(OH)D by approximately 10 ng/mL 4
- Vitamin D3 (cholecalciferol) is preferred over vitamin D2 (ergocalciferol) for long-term supplementation 4, 1
- Daily dosing is physiologic, but weekly or monthly dosing can be similarly effective 4
- Avoid single large annual doses (e.g., 500,000 IU) due to potential adverse effects 4
Special Populations
- Obesity: May require higher doses due to sequestration in adipose tissue 1
- Malabsorption syndromes: May require higher doses and more frequent monitoring 4, 1
- Chronic kidney disease: Requires specialized approaches 1
- Patients taking medications affecting vitamin D metabolism: May need dose adjustments 1
Target Levels and Monitoring
- Optimal vitamin D level: >30 ng/mL (75 nmol/L) 1
- Deficiency: <20 ng/mL (50 nmol/L) 1
- Insufficiency: 20-30 ng/mL (50-75 nmol/L) 1
- Safety range: 30-80 ng/mL 4
Safety Considerations
- Safe upper limit for daily intake: 4,000 IU for most adults 1
- Vitamin D toxicity typically occurs at levels above 150 ng/mL 1
- Monitor calcium and phosphorus levels when supplementing at higher doses 1
- Discontinue therapy if corrected total calcium exceeds 10.2 mg/dL 1
Common Pitfalls
- Underdosing: Many standard multivitamins contain only 400 IU, which may be insufficient for high-risk individuals
- Inconsistent supplementation: Intermittent use may not maintain adequate levels
- Overreliance on diet alone: Most diets provide insufficient vitamin D
- Seasonal variations: Vitamin D production from sunlight varies by season, latitude, and skin pigmentation
- Failure to recognize high-risk groups: Certain populations need higher supplementation doses
Recent research suggests that 2,000 IU/day may be more effective than lower doses for maintaining optimal vitamin D levels, especially during winter months 5, but this should be balanced against current guidelines recommending 800 IU/day for most adults 1.