What is the optimal ferritin range for a 36-year-old woman taking 60mg of iron chelate (iron(III) hydroxide polymaltose)?

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Optimal Ferritin Range for a 36-Year-Old Woman on Iron Chelate

The optimal ferritin range for a 36-year-old woman taking 60mg of iron chelate should be maintained between 50-100 ng/mL. 1, 2

Target Ferritin Levels Based on Clinical Guidelines

Iron supplementation therapy typically involves monitoring ferritin levels to ensure optimal iron status. For a woman of reproductive age taking iron supplementation:

  • Initial target: Achieve ferritin levels of at least 50 ng/mL 1
  • Maintenance target: Maintain ferritin in the 50-100 ng/mL range 1, 2
  • Upper limit: Avoid exceeding 500 ng/mL to prevent potential iron overload 2, 3

Monitoring Recommendations

For a woman taking iron chelate supplementation:

  • Check ferritin levels every 4-8 weeks during initial treatment 1
  • Once target levels are achieved, monitor every 3 months for the first year 2
  • Long-term follow-up should occur every 6-12 months 2

Clinical Considerations for Iron Chelate Therapy

Iron chelate (iron bisglycinate) has several advantages over traditional iron salts:

  • Better absorption profile than ferrous sulfate 4
  • Potentially fewer gastrointestinal side effects 4
  • May require lower dosing to achieve similar results 4

However, caution is warranted:

  • Long-term use of amino acid chelated iron without monitoring can potentially lead to iron overload 3
  • Regular ferritin monitoring is essential, especially if supplementation continues beyond one year 3

Interpreting Ferritin Results

When evaluating ferritin levels:

  • <30 ng/mL: Indicates iron deficiency in women without inflammation 2
  • 30-50 ng/mL: Suboptimal iron stores; continue supplementation 2, 5
  • 50-100 ng/mL: Optimal maintenance range 1
  • >500 ng/mL: Consider discontinuing supplementation to avoid iron overload 2, 3

Important Caveats

  • Ferritin is an acute phase reactant; inflammation can falsely elevate levels 2, 6
  • If inflammation is suspected (check CRP), ferritin values may need to be interpreted differently 2
  • Traditional laboratory reference ranges for women may underdiagnose iron deficiency 5
  • Recent evidence suggests that physiologic ferritin "cutoff" should be around 50 ng/mL, not the lower values often used in laboratory reference ranges 5

Conclusion

For a 36-year-old woman taking 60mg of iron chelate, aim for ferritin levels between 50-100 ng/mL, with regular monitoring to ensure levels don't exceed 500 ng/mL. This range optimizes iron status while minimizing risks of both iron deficiency and potential iron overload.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Iron Deficiency Anemia Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Sex, lies, and iron deficiency: a call to change ferritin reference ranges.

Hematology. American Society of Hematology. Education Program, 2023

Research

Serum or plasma ferritin concentration as an index of iron deficiency and overload.

The Cochrane database of systematic reviews, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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