What are the symptoms of orbital cellulitis?

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From the Guidelines

Orbital cellulitis is a medical emergency that presents with symptoms such as painful eye swelling, redness of the eyelids and surrounding tissues, limited or painful eye movement, fever, decreased vision, bulging of the eye (proptosis), and inability to fully open the eye, as noted in the most recent study 1.

Symptoms of Orbital Cellulitis

The symptoms of orbital cellulitis can be categorized into several key areas, including:

  • Painful eye swelling and redness of the eyelids and surrounding tissues
  • Limited or painful eye movement
  • Fever
  • Decreased vision
  • Bulging of the eye (proptosis)
  • Inability to fully open the eye
  • Double vision, which may occur as the infection affects eye muscle function
  • Headache, lethargy, and reduced pupillary response to light in severe cases

Causes and Complications

Orbital cellulitis results from bacterial infection spreading to the tissues surrounding the eye, often originating from sinusitis, trauma, or skin infections, with Staphylococcus and Streptococcus species being common causative organisms 1. Delayed treatment can lead to serious complications, including vision loss, cavernous sinus thrombosis, brain abscess, or meningitis.

Diagnosis and Treatment

The primary role of imaging is to differentiate preseptal cellulitis from postseptal cellulitis and abscess, and to identify underlying sinusitis and intracranial complications of orbital infections 1. Prompt treatment with intravenous antibiotics, such as vancomycin plus ceftriaxone or ampicillin-sulbactam, is essential to prevent serious complications and improve outcomes 1.

From the Research

Symptoms of Orbital Cellulitis

The symptoms of orbital cellulitis include:

  • Erythema and edema of the eyelids 2, 3, 4, 5
  • Vision loss 2, 3, 6, 5
  • Fever 2, 3, 4, 5
  • Headache 2, 3, 5
  • Proptosis 2, 3, 4, 5
  • Chemosis 2, 3, 4, 5
  • Diplopia 2, 3, 5
  • Blurred vision 3, 6, 5
  • Ophthalmoplegia 5
  • Diffuse lid edema with or without erythema 5

Causes and Risk Factors

Orbital cellulitis can be caused by:

  • Sinus infection 2, 3, 6, 5
  • Infection of the eyelids or face 2, 3
  • Hematogenous spread from distant locations 2, 3
  • Trauma 3, 6, 5
  • Retained foreign bodies 3
  • Preexisting dental infections 5
  • Dental procedures 5
  • Maxillofacial surgeries 5
  • Open Reduction and Internal Fixation (ORIF) 5
  • Retinal buckling procedures 5

Diagnosis and Treatment

Diagnosis of orbital cellulitis can be made using:

  • Computed tomography (CT) imaging 2, 6, 5
  • Magnetic resonance imaging (MRI) 5 Treatment of orbital cellulitis includes:
  • Antibiotic coverage 2, 3, 6, 5
  • Surgical intervention when needed 2, 3, 6, 5
  • Drainage of pus and establishment of ventilation to the sinus if the infection is secondary to sinus infection 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Orbital cellulitis.

Survey of ophthalmology, 2018

Research

The hot orbit: orbital cellulitis.

Middle East African journal of ophthalmology, 2012

Research

Facial and periorbital cellulitis with orbital involvement.

Journal of the European Academy of Dermatology and Venereology : JEADV, 2002

Research

Bacterial orbital cellulitis - A review.

Indian journal of ophthalmology, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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