Another Name for Lantus (Insulin Glargine)
Lantus (insulin glargine) is also available under brand names including Basaglar and Toujeo. 1, 2
Understanding Insulin Glargine
Insulin glargine is a long-acting basal insulin analog that provides:
- Duration of action up to 24 hours 1
- No pronounced peak in insulin levels 3
- Relatively constant basal insulin supply 3
The American Diabetes Association guidelines identify several formulations of insulin glargine:
- Lantus (original formulation, 100 U/mL) 1
- Basaglar (follow-on biologic/biosimilar, 100 U/mL) 1
- Toujeo (concentrated formulation, 300 U/mL) 4, 5
Pharmacological Properties
Insulin glargine has unique properties compared to other insulins:
These properties make it suitable for once-daily dosing as a basal insulin to control fasting glucose and provide background insulin throughout the day 2.
Clinical Applications
Insulin glargine is indicated for:
It can be used:
- In combination with rapid-acting insulin for type 1 diabetes 3
- With oral antidiabetic medications in type 2 diabetes 3
- As a once-daily injection that can be administered at any time of day (preferably at the same time each day) 2
Important Considerations
When transitioning between different insulin glargine products:
- Toujeo (300 U/mL) and Lantus (100 U/mL) are not bioequivalent and may require dose adjustments 4
- Patients switching from one formulation to another should monitor blood glucose levels more frequently 4
- Insulin glargine should not be mixed with other insulins due to its acidic pH 6
Practical Information
Insulin glargine is available in:
Proper storage is essential:
- Unopened insulin glargine should be refrigerated (36°F to 46°F) 2
- Once opened, it can be stored at room temperature below 86°F for up to 28 days 2
By understanding the different brand names and formulations of insulin glargine, healthcare providers can better communicate with patients about their medication regimen and ensure appropriate use.