Multiple Sclerosis (MS) itself: Increased sensory sensitivity can be a direct result of the demyelination process in MS, affecting the transmission of sensory signals in the central nervous system.

Trigeminal Neuralgia: A condition that can occur in MS patients, characterized by sudden, severe, shock-like or stabbing pain in parts of the face, which could be perceived as increased sensory sensitivity.
Neuropathic Pain: A common symptom in MS patients, resulting from damage to the nervous system, which can manifest as increased sensitivity to touch or other stimuli.
Spasticity: While primarily associated with motor symptoms, spasticity in MS can also lead to abnormal sensory perceptions due to the altered muscle tone and spasms.

Syringomyelia: A condition characterized by the formation of a fluid-filled cavity or syrinx within the spinal cord, which can cause sensory disturbances, including increased sensitivity, and can be associated with or mimic MS symptoms.
Vitamin B12 Deficiency: A deficiency that can cause neurological symptoms similar to MS, including numbness, tingling, and increased sensitivity, and is important to diagnose due to its treatable nature.
Cervical Spondylosis: A condition affecting the cervical spine that can cause neurological symptoms, including sensory changes, due to compression of the spinal cord or nerve roots.

Adrenomyeloneuropathy (AMN): A rare, inherited disorder affecting the myelin sheath of the nervous system, which can present with symptoms similar to MS, including increased sensory sensitivity.
Leukodystrophies: A group of rare, genetic disorders characterized by the progressive degeneration of the white matter in the brain, which can cause a variety of neurological symptoms, including sensory disturbances.
Tangier Disease: A rare inherited disorder affecting the nervous system, among other systems, which can lead to neuropathy and potentially increased sensory sensitivity, though it is more commonly associated with other symptoms.