Management of Hypoglycemic Emergencies
For hypoglycemic emergencies, immediately administer oral glucose (15-20g) for conscious patients who can swallow, or glucagon injection for unconscious patients, followed by calling emergency services for severe cases. 1, 2, 3
Assessment and Initial Management
Conscious Patient with Mild-Moderate Hypoglycemia
- If patient is conscious, able to follow commands and swallow safely:
- Administer 15-20g of fast-acting oral glucose 1, 2
- Preferred options (in order):
- Glucose tablets (most effective) 1
- 4 oz (120 mL) of fruit juice or regular soda
- 1 tablespoon of honey or sugar dissolved in water
- Recheck blood glucose after 15 minutes 1, 2
- If blood glucose remains <70 mg/dL, repeat treatment with another 15-20g of glucose 1, 2
- Wait at least 10-15 minutes before calling EMS or re-treating with additional oral sugars 1
- Once blood glucose normalizes, provide a meal or snack with protein and complex carbohydrates to prevent recurrence 2
Unconscious Patient or Severe Hypoglycemia
- If patient is unconscious, having seizures, or unable to swallow safely:
- Call EMS immediately 1
- Administer glucagon via injection 3:
- Adults and children >25kg or ≥6 years: 1mg subcutaneously or intramuscularly into upper arm, thigh, or buttocks
- Children <25kg or <6 years: 0.5mg subcutaneously or intramuscularly
- May repeat dose after 15 minutes if no response while waiting for emergency assistance 3
- Position patient on their side to prevent aspiration
- Monitor vital signs until EMS arrives
- Once patient regains consciousness and can swallow safely, provide oral carbohydrates to restore liver glycogen and prevent recurrence 3
Special Considerations
Hospital Setting
- Implement standardized hypoglycemia protocol 2:
- Nurse-initiated treatment protocol for blood glucose <70 mg/dL
- Documentation of hypoglycemic episodes
- Review of treatment regimens to prevent further episodes
Pediatric Patients
- Children may be uncooperative with oral glucose administration
- Consider sublingual glucose administration for uncooperative children 1
- Children are particularly vulnerable due to reduced ability to recognize symptoms 2
Elderly Patients
- More vulnerable to hypoglycemia due to reduced symptom recognition 2
- May require closer monitoring and more conservative glucose targets
Follow-up Care
- After successful treatment of hypoglycemia:
- Identify and address the cause (medication dosing, missed meals, exercise)
- Consider temporarily raising glycemic targets to avoid recurrence 2
- Educate patient and family members about recognition and treatment of hypoglycemia
- Ensure patient has glucagon emergency kit and family members know how to use it 2, 3
- Recommend wearing medical alert identification 2
Common Pitfalls to Avoid
- Delayed treatment: Hypoglycemia is an emergency; treat immediately when recognized 3
- Inadequate monitoring: Always recheck glucose 15 minutes after treatment 1, 2
- Premature discharge: Ensure blood glucose has stabilized and patient has consumed a meal before leaving 4
- Overlooking the cause: Identify and address the underlying cause to prevent recurrence
- Insufficient follow-up: Less than 8% of patients treated for hypoglycemia and left at home need secondary treatment within 72 hours, but follow-up is still important 4
By following this algorithmic approach to hypoglycemia management, healthcare providers can effectively treat this common but potentially dangerous condition while minimizing complications and preventing recurrence.