What are the guidelines for inpatient treatment of stroke?

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Last updated: August 13, 2025View editorial policy

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Inpatient Stroke Management Guidelines

All acute stroke patients should be admitted to a specialized stroke unit as soon as possible, ideally within 6 hours of hospital arrival, to significantly reduce mortality and improve functional outcomes. 1, 2

Stroke Unit Care

A stroke unit is defined as a geographically defined hospital unit dedicated to the management of stroke patients with the following key components:

  • Core interprofessional team with stroke expertise including:
    • Physicians with stroke expertise
    • Specialized nursing staff
    • Occupational therapists
    • Physiotherapists
    • Speech-language pathologists
    • Social workers
    • Clinical nutritionists/dietitians
    • Hospital pharmacists 1, 2

For facilities without a dedicated stroke unit, focus care on priority elements including:

  • Clustering stroke patients together
  • Forming an interprofessional team
  • Implementing stroke care protocols
  • Conducting regular case rounds
  • Providing patient education 1

Initial Assessment and Monitoring

  • Complete interdisciplinary team assessment within 48 hours of admission 2
  • Perform neurovascular imaging without delay for all stroke patients 2
  • Consider prolonged ECG monitoring (up to 30 days) for patients with suspected embolic stroke of undetermined source 1, 2
  • Monitor vital signs including:
    • Temperature every 4 hours for first 48 hours, then as per ward routine 1
    • For temperature >37.5°C, increase monitoring frequency, initiate temperature-reducing measures, and investigate possible infections 1

Venous Thromboembolism (VTE) Prophylaxis

For patients at high risk of VTE:

  • Start thigh-high intermittent pneumatic compression (IPC) devices or pharmacological prophylaxis immediately if no contraindications 1
  • If using IPC, apply within first 24 hours and continue until patient becomes independently mobile, is discharged, or reaches 30 days 1
  • Consider low-molecular-weight heparin (enoxaparin) for ischemic stroke patients; use unfractionated heparin for those with renal failure 1
  • Anti-embolism stockings alone are not recommended 1
  • Early mobilization and adequate hydration should be encouraged 1

Mobilization Protocol

  • All patients should be assessed by rehabilitation professionals within 48 hours of admission 1
  • Do not initiate frequent, out-of-bed activity within 24 hours of stroke onset 1
  • Begin mobilization between 24-48 hours after stroke onset if no contraindications 1
  • Contraindications include:
    • Recent arterial puncture for interventional procedures
    • Unstable medical conditions
    • Low oxygen saturation
    • Lower limb fracture or injury 1

Continence Management

  • Avoid indwelling catheters due to risk of urinary tract infection 1
  • If used, assess catheters daily and remove as soon as possible 1
  • Screen all stroke patients for urinary incontinence/retention and fecal incontinence/constipation 1
  • Use portable ultrasound to assess post-void residual 1
  • Implement bladder training programs for incontinent patients 1
  • Establish appropriate intermittent catheterization schedules based on post-void residual 1
  • Implement bowel management programs for patients with persistent constipation or bowel incontinence 1

Discharge Planning

  • Begin discharge planning during initial admission assessment 1
  • Continue planning throughout hospitalization 1
  • Anticipate discharge needs to facilitate smooth transitions 1
  • Conduct daily/bi-weekly patient care rounds with the interprofessional team 1
  • Provide formal, coordinated patient and family education 1

In-Hospital Stroke

  • Hospital inpatients who develop stroke should be assessed promptly and receive appropriate access to acute stroke care 1, 2
  • Implement protocols for rapid recognition and management of in-hospital strokes 2

Common Pitfalls and Caveats

  1. Delayed Recognition: Failure to recognize stroke symptoms promptly can lead to worse outcomes, especially for in-hospital strokes 2

  2. Inadequate VTE Prophylaxis: Anti-embolism stockings alone are insufficient; use IPC devices or pharmacological prophylaxis 1

  3. Premature Mobilization: Very early mobilization (within 24 hours) may be harmful based on recent evidence 1

  4. Prolonged Catheterization: Indwelling catheters increase infection risk and should be removed as soon as possible 1

  5. Lack of Standardized Protocols: Failure to implement standardized protocols for stroke assessment and management can lead to worse outcomes 2

By following these evidence-based guidelines for inpatient stroke management, healthcare providers can optimize recovery, prevent complications, and improve outcomes for patients with acute stroke.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Acute Stroke Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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