What are the types of blindness associated with optic radiation lesions?

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Last updated: March 7, 2025View editorial policy

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From the Guidelines

Optic radiation lesions are associated with homonymous bilateral field defects, including homonymous hemianopsia, quadrantanopia, and central scotoma, as evidenced by the most recent study in 2023 1. The types of blindness associated with optic radiation lesions can be categorized into:

  • Homonymous hemianopsia, which affects the same half of the visual field in both eyes, either right or left
  • Quadrantanopia, which affects a quarter of the visual field, either superior or inferior
  • Central scotoma, which affects the central area of the visual field, and can be unilateral or bilateral These visual field defects occur due to the topographic organization of optic radiations, which carry visual information from the lateral geniculate nucleus to the primary visual cortex. According to the 2023 study 1, the ICD-10 CM codes for these conditions include H53.411, H53.412, and H53.413 for central scotoma, and H53.461, H53.462, and H53.469 for homonymous bilateral field defects. It is essential to code any associated underlying cause of the blindness first, as specified in the ICD-10 CM guidelines 1. The specific types of blindness associated with optic radiation lesions are:
  • Homonymous bilateral field defects, which can be further classified into:
  • Homonymous hemianopsia
  • Quadrantanopia
  • Central scotoma, which can be unilateral or bilateral.

From the Research

Types of Blindness Associated with Optic Radiation Lesions

The types of blindness associated with optic radiation lesions can be categorized based on the location and extent of the lesion.

  • Homonymous hemianopia: a visual field defect that affects the same side of the visual field in both eyes 2, 3
  • Homonymous quadrantanopia: a visual field defect that affects one quadrant of the visual field in both eyes 2, 3
  • Macular sparing: a condition where the central part of the visual field is spared despite damage to the optic radiation 2, 3
  • Incongruous hemianopia: a visual field defect that affects different parts of the visual field in each eye 3
  • Peripheral homonymous hemianopia: a visual field defect that affects the peripheral part of the visual field in both eyes 4
  • Homonymous paracentral scotomas: a visual field defect that affects the central part of the visual field in both eyes 3

Factors Influencing the Type of Blindness

The type of blindness associated with optic radiation lesions can be influenced by several factors, including:

  • Location of the lesion: lesions in different parts of the optic radiation can cause different types of visual field defects 2, 3, 4
  • Extent of the lesion: the extent of the lesion can affect the severity and type of visual field defect 2, 3
  • Depth of the lesion: deep lesions can affect the deeper strata of the optic radiation, causing different types of visual field defects 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[Campimetric changes in optic radiation lesions].

Acta neurologica latinoamericana, 1977

Research

Visual Field Defect Patterns Associated With Lesions of the Retrochiasmal Visual Pathway.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2022

Research

Peripheral homonymous hemianopia: correlation between lesion location and visual field defects by means of cytoarchitectonic probabilistic maps.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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