What is the difference between Vaseline (petroleum jelly) and Aquaphor (multi-purpose ointment)?

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From the Research

Differences between Vaseline and Aquaphor

  • Vaseline, also known as petroleum jelly, is a topical agent used for its moisturizing properties 1
  • Aquaphor, on the other hand, is a multi-purpose ointment used for wound care and skin protection 2, 3
  • A study compared the clinical efficacy and cost-efficacy of Aquaphor to other barrier repair creams in treating mild-to-moderate atopic dermatitis, and found that Aquaphor was as effective and at least 47 times more cost-effective 2
  • Petroleum jelly, such as Vaseline, has been shown to accelerate barrier recovery and permeate throughout the stratum corneum interstices, allowing for normal barrier recovery despite its occlusive properties 4
  • In postoperative wound care, petroleum jelly and Aquaphor are commonly used topical emollients, with petroleum jelly being the most commonly used immediately postoperatively and at home 3

Uses and Benefits

  • Vaseline is used as a moisturizer, patch test instrument, vehicle for medicated ointments, and wound care essential 1
  • Aquaphor is used for wound care, skin protection, and as a treatment for mild-to-moderate atopic dermatitis 2, 3
  • Both Vaseline and Aquaphor have been used to keep wounds moist and promote healing, with petroleum jelly being recommended by 69.4% of respondents in a survey of Mohs surgeons 3

Comparison of Properties

  • Petroleum jelly has been shown to have a number of benefits, including its ability to accelerate barrier recovery and its low risk for contact allergy 4, 3
  • Aquaphor, on the other hand, has been shown to be as effective as other barrier repair creams in treating mild-to-moderate atopic dermatitis, and is at least 47 times more cost-effective 2

References

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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