Differential Diagnosis for Large Back Mole with Red Rash Surrounding it
- Single most likely diagnosis
- Melanoma: This is the most concerning and likely diagnosis given the description of a large mole with a red rash surrounding it. The ABCDE rule (Asymmetry, Border, Color, Diameter, Evolving) is often used to evaluate suspicious moles, and a red rash could indicate inflammation or regression, which are signs of potential malignancy.
- Other Likely diagnoses
- Seborrheic Keratosis with inflammation: This is a common benign skin growth that can become inflamed, leading to a red rash around the lesion.
- Dermatofibroma: A benign skin growth that can sometimes become inflamed or irritated, causing a red rash.
- Pyogenic Granuloma: A benign vascular lesion that can appear as a red, bleeding bump, sometimes surrounded by a red rash.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
- Merkel Cell Carcinoma: A rare and aggressive skin cancer that can present as a firm, painless nodule or bump, sometimes with a red rash.
- Angiosarcoma: A rare and aggressive cancer of the blood vessels that can present as a red, bruise-like lesion or rash.
- Lymphoma (Cutaneous T-Cell Lymphoma): A type of cancer that affects the immune system and can present with skin lesions, including red rashes.
- Rare diagnoses
- Kaposi's Sarcoma: A rare cancer that can cause red, purple, or brown lesions on the skin, often associated with immune system suppression.
- Leiomyosarcoma: A rare cancer of smooth muscle cells that can present as a firm, painless nodule or bump, sometimes with a red rash.
- Metastatic cancer: In rare cases, a red rash surrounding a mole could be a sign of metastatic cancer, such as breast or lung cancer that has spread to the skin.