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Differential Diagnosis for Itching Hands

Single Most Likely Diagnosis

  • Dry Skin (Xerosis): This is the most common cause of itching hands, especially during dry or cold weather. It can be due to excessive washing, harsh soaps, or a lack of moisturizing.

Other Likely Diagnoses

  • Contact Dermatitis: This is a skin reaction that occurs after contact with an irritant or allergen, leading to itching, redness, and sometimes blistering. Common culprits include soaps, detergents, and certain metals.
  • Eczema (Atopic Dermatitis): A chronic skin condition characterized by itchy, inflamed skin. It often affects the hands, especially in individuals with a history of allergies or asthma.
  • Psoriasis: An autoimmune condition that speeds up the life cycle of skin cells, causing cells to build up rapidly on the surface of the skin. The extra skin cells form scales and red patches that itch and burn.

Do Not Miss Diagnoses

  • Scabies: A parasitic infection caused by the scabies mite, which burrows into the skin and causes intense itching, especially at night. It's highly contagious and requires prompt treatment.
  • Lymphoma: Certain types of lymphoma, such as mycosis fungoides, can cause itching skin lesions. Although rare, missing this diagnosis could have severe consequences.
  • Hepatic or Renal Disease: Itching can be a symptom of liver or kidney disease, such as primary biliary cirrhosis or chronic kidney disease. These conditions require medical attention to prevent further complications.

Rare Diagnoses

  • Keratosis Pilaris: A harmless condition that causes small, rough patches on the skin, often accompanied by itching. It's more common on the arms, but can occur on the hands.
  • Dyshidrotic Eczema: A type of eczema that causes small, itchy blisters on the hands and feet.
  • Aquagenic Pruritus: A rare condition characterized by itching that occurs after exposure to water, without any visible skin lesions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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