Key Components of Post-Cardiac Arrest Care
Post-cardiac arrest care requires a comprehensive, structured, multidisciplinary system of care implemented consistently to optimize survival and neurological recovery, including therapeutic hypothermia, hemodynamic optimization, ventilatory support, and identification and treatment of the precipitating cause of arrest. 1
Initial Objectives
- Optimize cardiopulmonary function and vital organ perfusion
- Transport to appropriate facility with comprehensive post-cardiac arrest capabilities
- Identify and treat precipitating causes of arrest to prevent recurrence 1
Immediate Management
Airway and Ventilation
- Secure advanced airway (avoid ties that pass circumferentially around neck)
- Elevate head of bed 30° if tolerated
- Avoid excessive ventilation:
- Start at 10-12 breaths/min
- Titrate to PETCO2 of 35-40 mmHg
- Maintain oxygen saturation ≥94%
- Titrate FiO2 to minimum necessary 1
Hemodynamic Support
- IV bolus: 1-2 L normal saline or lactated Ringer's
- For hypotension (SBP <90 mmHg), use:
- Epinephrine IV: 0.1-0.5 mcg/kg/min
- Dopamine IV: 5-10 mcg/kg/min
- Norepinephrine IV: 7-35 mcg/min (for 70-kg adult) 1
Essential Monitoring
- Continuous cardiac telemetry
- Pulse oximetry
- Quantitative capnography
- Arterial blood pressure (intra-arterial when possible)
- Continuous core temperature (esophageal, bladder, or rectal)
- Urine output
- Arterial blood gases
- Serum lactate
- Blood glucose, electrolytes, complete blood count, coagulation profile 1
Subsequent Management
Temperature Management
- Control body temperature to optimize survival and neurological recovery
- Implement therapeutic hypothermia as part of structured interventions 1
Cardiovascular Care
- Obtain 12-lead ECG as soon as possible after ROSC
- Identify and treat acute coronary syndromes
- Consider immediate coronary angiography for patients with ST elevation 1
- Perform echocardiography to identify myocardial dysfunction 1
Neurological Care
- Perform serial neurological examinations
- Consider continuous EEG monitoring due to high incidence of post-ROSC seizures
- Brain imaging (CT or MRI) when indicated 1
Addressing Reversible Causes
- Systematically evaluate and treat:
- Hypovolemia
- Hypoxia
- STEMI
- Acidosis
- Hypo/hyperkalemia
- Hypothermia
- Tension pneumothorax
- Cardiac tamponade
- Toxins
- Pulmonary thrombosis
- Coronary thrombosis 1
Common Pitfalls to Avoid
- Hyperventilation: Leads to cerebral vasoconstriction and decreased cerebral perfusion
- Hypotension: Failure to maintain adequate blood pressure can worsen neurological outcomes
- Delayed identification of treatable causes: Systematically evaluate for all reversible causes
- Inadequate monitoring: Comprehensive monitoring is essential to guide therapy
- Premature prognostication: Avoid withdrawal of care in the absence of definite prognostic signs 2
System of Care Considerations
- Implement a coordinated and integrated response from prehospital, emergency department, and ICU providers 1
- Consider transfer to specialized cardiac arrest centers for facilities with limited resources 3
- Participate in national quality-improvement initiatives 2
Post-cardiac arrest care is resource-intensive and requires simultaneous evaluation for underlying causes while providing intensive management to prevent further end-organ damage, particularly to the central nervous system 3. The implementation of a post-cardiac arrest care bundle that incorporates therapeutic hypothermia and early hemodynamic optimization has been shown to improve outcomes 4.