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Differential Diagnosis for Painful Lump under Right Abdomen

Single Most Likely Diagnosis

  • Appendicitis: This is a common condition that presents with pain, often starting near the belly button and then moving to the lower right abdomen, and can be associated with a palpable lump if an appendicular mass forms. The pain is usually severe and accompanied by other symptoms like fever and nausea.

Other Likely Diagnoses

  • Inguinal Hernia: A hernia in the groin area can cause a painful lump, especially if it becomes incarcerated or strangulated. The lump is usually more prominent with coughing or straining.
  • Ovarian Cyst (in females): Ovarian cysts can cause abdominal pain and a palpable mass. If the cyst ruptures or torsion occurs, the pain can become severe.
  • Diverticulitis: Inflammation of a diverticulum in the colon can cause pain, usually on the left side but can occur on the right, and may be associated with a palpable mass if an abscess forms.

Do Not Miss Diagnoses

  • Ectopic Pregnancy (in females): Although less common, an ectopic pregnancy can present with abdominal pain and a mass. It is a medical emergency due to the risk of rupture and severe bleeding.
  • Intestinal Obstruction: Obstruction of the intestine can cause severe abdominal pain, vomiting, and a palpable mass if a closed-loop obstruction occurs. It requires prompt surgical intervention.
  • Ruptured Aneurysm (e.g., abdominal aortic aneurysm): While less common, a ruptured aneurysm can present with severe abdominal pain and a palpable mass. It is a life-threatening condition requiring immediate medical attention.

Rare Diagnoses

  • Lymphoma: Abdominal lymphoma can cause pain and a palpable mass due to lymph node enlargement. It is less common and usually diagnosed after other more frequent causes have been ruled out.
  • Soft Tissue Sarcoma: A rare type of cancer that can occur in the abdominal wall, presenting as a painful lump. Diagnosis often requires imaging and biopsy.
  • Psoas Abscess: An abscess in the psoas muscle can cause lower abdominal or back pain and a palpable mass. It is relatively rare and often associated with underlying conditions like osteomyelitis or spinal infection.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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