Is it safe to receive the Measles, Mumps, and Rubella (MMR) vaccine at 40 years old with diabetes mellitus?

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Last updated: March 7, 2025View editorial policy

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From the Guidelines

It is generally safe for a 40-year-old with diabetes to receive the MMR (measles, mumps, rubella) vaccine, as having diabetes does not typically create any contraindications for receiving this vaccine. The MMR vaccine is an inactivated vaccine that does not contain live viruses, making it safe for most adults with chronic conditions like diabetes 1. In fact, people with chronic conditions like diabetes may benefit particularly from vaccination protection since they can be at higher risk for complications from vaccine-preventable diseases.

Key Considerations

  • Before vaccination, you should inform your healthcare provider about your diabetes status, current medications, and any previous adverse reactions to vaccines.
  • The most common side effects of the MMR vaccine are mild and temporary, including soreness at the injection site, low-grade fever, and mild rash.
  • Your blood glucose levels may fluctuate slightly following vaccination due to the immune response, so monitoring your levels more frequently for 1-2 days after vaccination is advisable.
  • Stay hydrated and maintain your regular diabetes management routine after receiving the vaccine.

Recommendations

  • Adults born in 1957 or later should have documentation of 1 or more doses of MMR vaccine unless they have a medical contraindication to the vaccine, or laboratory evidence of immunity to each of the 3 diseases 1.
  • A routine second dose of MMR vaccine, administered a minimum of 28 days after the first dose, is recommended for adults who are students in postsecondary educational institutions, work in a health care facility, or plan to travel internationally 1.

Conclusion Not Applicable - Direct Answer Only

As the most recent and highest quality study available is from 2013, the information provided in this study will be used to guide the recommendation 1.

From the Research

Safety of MMR Vaccine in Diabetic Patients

  • The safety of receiving the Measles, Mumps, and Rubella (MMR) vaccine at 40 years old with diabetes mellitus is not directly addressed in the provided studies.
  • However, studies suggest that vaccination in diabetic patients is generally safe, as long as there are no other contraindications, such as allergy to vaccine components or severe acute febrile illness 2.
  • Inactivated vaccines are preferred for diabetic patients, as they are safe even in immunocompromised individuals 3.
  • Live attenuated vaccines, such as the MMR vaccine, should be carefully considered and measured against the risks of exposure to each specific infectious agent in patients with unstable glycaemia and significantly impaired immune system due to diabetes mellitus 2.

Vaccine Recommendations for Diabetic Patients

  • The basic vaccinations recommended for diabetics include immunizations against influenza, pneumococcal infections, tetanus, and viral hepatitis B 4.
  • Other vaccines, such as those against viral hepatitis A, tick-borne encephalitis, and meningococcal infections, may be administered after individual assessment of benefits and risks for the diabetic patient 4.
  • Influenza vaccination has been shown to be associated with reduced cardiovascular mortality in adults with diabetes 5.

MMR Vaccine and Diabetes

  • One study found no increased risk of type 1 diabetes associated with the measles-mumps-rubella vaccine 6.
  • However, this study did not specifically address the safety of the MMR vaccine in diabetic patients, and more research is needed to determine the safety of the MMR vaccine in this population.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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