Interpretation of eGFR 110 and Creatinine 28
An eGFR of 110 mL/min/1.73m² with a creatinine of 28 μmol/L (approximately 0.32 mg/dL) indicates excellent kidney function and requires no intervention, as these values are within the normal to high-normal range.
Understanding These Values
eGFR Interpretation
- An eGFR of 110 mL/min/1.73m² is considered normal to high-normal kidney function 1
- Normal GFR is approximately 130 mL/min/1.73m² for men and 120 mL/min/1.73m² for women 1
- According to KDIGO guidelines, eGFR ≥90 mL/min/1.73m² is classified as G1 (normal kidney function) 1
Creatinine Interpretation
- A serum creatinine of 28 μmol/L (approximately 0.32 mg/dL) is actually lower than the typical reference range for most adults
- This very low creatinine level could reflect:
- Low muscle mass
- Excellent kidney function
- Possible laboratory error (worth confirming if uncertain)
Clinical Significance
What These Values Mean for Your Health
- These values indicate that your kidneys are filtering blood very efficiently
- An eGFR >60 mL/min/1.73m² generally indicates normal or mildly decreased kidney function 2
- Your high eGFR (110) suggests you do not have chronic kidney disease
Important Considerations
Low creatinine levels can sometimes be seen in:
- People with low muscle mass
- Elderly individuals
- Those with certain medical conditions affecting muscle
- Pregnant women
High eGFR values (>90 mL/min/1.73m²) are typically normal but can sometimes be seen in:
- Early diabetes (hyperfiltration)
- Pregnancy
- Very healthy individuals
Recommendations
What You Should Do
- No immediate action needed for these kidney function values
- Continue routine health maintenance:
- Maintain adequate hydration
- Follow a balanced diet
- Exercise regularly
- Avoid nephrotoxic medications when possible 1
Follow-up Considerations
- Annual monitoring of kidney function is generally sufficient for individuals with normal eGFR and no risk factors 1
- If you have risk factors for kidney disease (diabetes, hypertension, family history), your healthcare provider may recommend more frequent monitoring
Important Caveats
- eGFR can fluctuate based on various factors including hydration status, recent exercise, and certain medications 1
- A single measurement should not be over-interpreted; trends over time are more meaningful
- The eGFR calculation has limitations and may not perfectly reflect kidney function in all individuals, particularly those with unusual body composition 3
- For complete kidney health evaluation, urine albumin-to-creatinine ratio (ACR) should also be measured to assess for albuminuria 1
Remember that while these values indicate excellent kidney function, maintaining a healthy lifestyle remains important for long-term kidney health.