From the Guidelines
Tamiflu (oseltamivir) can be taken with Eliquis (apixaban) as there are no significant drug interactions between these medications. You can continue your regular Eliquis dosing while taking Tamiflu for influenza treatment or prevention. While both medications are processed by the liver, they use different metabolic pathways, which minimizes the risk of interaction 1. Tamiflu works by inhibiting the influenza virus's ability to spread within your body, while Eliquis is an anticoagulant that prevents blood clots. As with any medication combination, it's essential to monitor for any unusual bleeding or bruising, which could potentially be a side effect of Eliquis. If you experience any concerning symptoms while taking these medications together, contact your healthcare provider promptly. Always inform all your healthcare providers about all medications you're taking to ensure safe treatment.
The provided evidence does not suggest any significant interactions between oseltamivir and apixaban. The study by 1 discusses the metabolism and clearance of apixaban, which is primarily metabolized via the liver, but does not indicate any interaction with oseltamivir. Another study 1 focuses on the use of direct oral anticoagulants, including apixaban, in the treatment of heparin-induced thrombocytopenia, but does not mention oseltamivir.
Key points to consider when taking these medications together include:
- Monitoring for unusual bleeding or bruising
- Informing all healthcare providers about all medications being taken
- Understanding the different mechanisms of action of Tamiflu and Eliquis
- Being aware of the potential side effects of Eliquis, such as bleeding or bruising.
It is crucial to follow the recommended dosing and administration instructions for both medications and to seek medical attention if any concerns or symptoms arise.
From the Research
Oseltamivir (Tamiflu) and Apixaban (Eliquis) Interactions
There are no research papers provided that directly discuss the contraindications or drug interactions between Oseltamivir (Tamiflu) and Apixaban (Eliquis).
Available Information on Oseltamivir
- Oseltamivir is a prodrug of oseltamivir carboxylate, a potent and selective inhibitor of the neuraminidase glycoprotein essential for replication of influenza A and B viruses 2.
- Oseltamivir has been shown to be effective in the treatment and prevention of epidemic influenza infection in adults, adolescents, and children 2, 3, 4.
- The drug is generally well tolerated, with a similar adverse event profile to placebo, but it can cause nausea, vomiting, and increase the risk of headaches and renal and psychiatric syndromes 3, 5.
Limitations
- The provided studies do not discuss the interaction between Oseltamivir and Apixaban.
- There is no information available on the contraindications or drug interactions between Oseltamivir and Apixaban based on the given evidence.