Acetaminophen Dosing for Children
Children should receive acetaminophen at a dose of 10-15 mg/kg every 4-6 hours, with no more than 5 doses in 24 hours. 1
Recommended Dosing Schedule
The appropriate dosing of acetaminophen for children depends on the child's weight rather than age, though age-based dosing is often provided on commercial products:
- Dose calculation: 10-15 mg/kg per dose 2, 3
- Frequency: Every 4-6 hours as needed 3
- Maximum doses per day: No more than 5 doses in 24 hours 3
- Maximum daily dose: Should not exceed 75 mg/kg/day or 4000 mg/day, whichever is less
Administration Guidelines
For Infants and Young Children
- Use weight-based dosing whenever possible (10-15 mg/kg)
- Use appropriate measuring devices for liquid formulations
- Do not use adult formulations for children under 12 years
- For infants under 3 months, consult a healthcare provider before administering
For Children 12 Years and Older
- Follow adult dosing instructions: 2 caplets (325 mg each) every 8 hours
- Do not exceed 6 caplets in 24 hours 1
- Do not use for more than 10 days unless directed by a doctor
Common Dosing Errors to Avoid
Research shows that dosing errors are common with acetaminophen administration:
- Up to 51% of parents give inaccurate doses of antipyretics 4
- 62% of acetaminophen doses given by parents are inaccurate 4
- Infants under 1 year are at highest risk for receiving incorrect doses (40% higher risk) 4
Common Pitfalls:
- Using age-based rather than weight-based dosing
- Using kitchen spoons instead of calibrated measuring devices
- Confusing different formulation concentrations
- Administering doses too frequently
- Exceeding the maximum daily dose
Safety Considerations
- Exceeding recommended doses can lead to liver toxicity
- Parents should record all dose times to avoid accidental overdosing
- When using multiple antipyretics (like acetaminophen and ibuprofen), carefully track each medication separately
- If fever persists beyond 72 hours despite appropriate dosing, seek medical attention
Alternative Options
If acetaminophen alone is insufficient for fever control, ibuprofen may be considered:
- Ibuprofen dosing: 10 mg/kg every 6-8 hours 5
- Some evidence suggests ibuprofen may be more effective for fever reduction 5
- In certain cases, alternating acetaminophen and ibuprofen may provide additional fever-free time, but requires careful tracking of doses 5
Remember that the goal of treatment is symptom relief and improved comfort, not necessarily normalization of temperature. Always consult a healthcare provider if fever is accompanied by concerning symptoms or persists despite appropriate treatment.