What is the treatment for a stomach virus?

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Last updated: August 14, 2025View editorial policy

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Treatment for Stomach Virus

The primary treatment for viral gastroenteritis is oral rehydration therapy, with continued normal feeding during illness to maintain gut integrity and resuming an age-appropriate usual diet during or immediately after rehydration. 1

Rehydration Therapy

  • Oral Rehydration Solution (ORS) is the cornerstone of treatment for viral gastroenteritis 1
  • For mild cases:
    • Half-strength apple juice followed by preferred liquids is effective 2
    • Commercial solutions like Pedialyte, Gatorade, or other oral rehydration solutions are all effective in correcting dehydration 3
  • For moderate dehydration:
    • Formal oral rehydration solutions are recommended 2
  • For severe dehydration:
    • Intravenous fluids may be necessary when patients cannot tolerate oral rehydration or have severe dehydration with signs of shock 2

Diet Management

  • Continue normal feeding during illness 1
  • Easily digestible foods (BRAT diet - bananas, rice, applesauce, toast) can be helpful during recovery 1
  • Breast milk should be continued for infants, as it may have protective effects against viral enteric infection 1
  • Be aware that mild lactose intolerance may develop after rotavirus infection (typically lasting 10-14 days) 1

Symptom Management

  • Antiemetics:

    • Ondansetron may be considered when vomiting is severe and preventing adequate oral rehydration, particularly in children >4 years 1
  • Antimotility Agents:

    • Should NOT be given to children <18 years with acute diarrhea 1
    • In adults, loperamide may be considered only after adequate hydration is achieved, but should be avoided with fever or inflammatory diarrhea 1
  • Other Medications:

    • Bismuth subsalicylate may reduce the duration of Norwalk virus infection (from 27 to 20 hours) 1

Prevention of Transmission

  • Vigorous handwashing with soap for at least 10 seconds after contact with ill persons 1, 4
  • Clean soiled surfaces promptly with appropriate disinfectants 4, 1
  • Isolate affected individuals for at least 2 days after symptom resolution 1
  • Handle soiled linens with minimum agitation and launder promptly with detergent 4
  • Food handlers should not prepare food for at least 2 days after resolution of illness 1

Special Considerations

High-Risk Patients

  • Elderly patients are at higher risk for dehydration and electrolyte imbalances and may require closer monitoring 1
  • Immunocompromised individuals may experience prolonged viral shedding and more severe disease, particularly with cytomegalovirus or adenovirus 1
    • For immunocompromised patients with CMV enteritis, ganciclovir treatment for 2-3 weeks (5 mg/kg bid IV), followed by maintenance therapy may be required 4
    • For adenovirus in severely ill immunocompromised patients, cidofovir may be considered despite its nephrotoxicity 4

Common Pitfalls to Avoid

  1. Delaying rehydration - This is the most critical intervention and should be started immediately
  2. Unnecessary dietary restrictions - Continuing normal feeding is recommended rather than fasting
  3. Overuse of antimotility agents - These can prolong viral shedding and are contraindicated in children
  4. Unnecessary antibiotic use - Antibiotics are ineffective against viral gastroenteritis and may worsen outcomes
  5. Inadequate infection control measures - Strict hygiene is essential to prevent transmission

Duration of Illness

Most viral gastroenteritis cases are self-limiting, with symptoms typically lasting:

  • Norovirus: 24-72 hours
  • Astrovirus: 1-4 days
  • Rotavirus: 4-7 days 1

Remember that viral shedding may continue for up to 3 weeks with norovirus, emphasizing the importance of continued hygiene measures even after symptoms resolve 1.

References

Guideline

Viral Gastroenteritis Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Gastroenteritis in Children.

American family physician, 2019

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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