From the Guidelines
The dose of regular insulin typically ranges from 0.4 to 1.0 units/kg/day, with 50% of the daily insulin given as basal and 50% as prandial, and can be adjusted based on individual needs and glycemic targets. When initiating or titrating prandial insulin, one approach is to start with a dose of 4 units per day or 10% of the basal insulin dose, and adjust as needed based on individualized needs and current glycemic management 1. The optimal time to administer prandial insulin varies based on the pharmacokinetics of the formulation, premeal blood glucose level, and carbohydrate consumption, and recommendations for prandial insulin dose administration should be individualized 1. Key factors to consider when determining the dose of regular insulin include:
- Total daily insulin requirements, which can be estimated based on weight
- The need for basal and prandial insulin, with typical doses ranging from 0.4 to 1.0 units/kg/day
- Individualized needs and glycemic targets, which may require adjustments to the dose and timing of insulin administration
- The potential for hypoglycemia, which should be carefully monitored and managed when initiating or titrating insulin therapy 1. In general, patients with type 1 diabetes require a planned regimen of insulin tailored to their individual needs, with the goal of keeping them safe and out of diabetic ketoacidosis and avoiding significant hypoglycemia, while also striving to reach their glycemic targets 1.
From the Research
Doses of Regular Insulin
There are no research papers to assist in answering this question. The provided studies do not mention the doses of regular insulin.