Differential Diagnosis for Easy Bruising in a Young Adult
Single Most Likely Diagnosis
- Vitamin C deficiency: A common and often overlooked cause of easy bruising, particularly in young adults with poor dietary habits. Vitamin C plays a crucial role in collagen synthesis, and its deficiency can lead to impaired blood vessel integrity.
Other Likely Diagnoses
- Medication side effects: Certain medications, such as anticoagulants, antiplatelet agents, and steroids, can increase the risk of bruising. A thorough medication history is essential to identify potential culprits.
- Hormonal fluctuations: Hormonal changes during menstruation, pregnancy, or menopause can affect blood vessel fragility and lead to easy bruising.
- Physical activity or trauma: Engaging in contact sports or experiencing minor trauma can cause bruising, especially in individuals with a tendency to bruise easily.
Do Not Miss Diagnoses
- Bleeding disorders (e.g., von Willebrand disease, hemophilia): Although less common, bleeding disorders can have severe consequences if left undiagnosed. A thorough family history and coagulation studies can help identify these conditions.
- Bone marrow failure or leukemia: These conditions can lead to thrombocytopenia or platelet dysfunction, resulting in easy bruising. A complete blood count (CBC) and peripheral smear can help detect these disorders.
- Liver disease: Liver dysfunction can impair coagulation factor production, leading to easy bruising. A liver function test (LFT) and coagulation studies can help diagnose liver disease.
Rare Diagnoses
- Ehlers-Danlos syndrome: A genetic disorder characterized by fragile blood vessels and easy bruising. Although rare, it is essential to consider this diagnosis in individuals with a family history or other characteristic features.
- Scurvy: A rare condition caused by severe vitamin C deficiency, leading to impaired collagen synthesis and easy bruising.
- Amyloidosis: A rare condition characterized by the deposition of abnormal proteins in blood vessels, leading to fragility and easy bruising.