Management of Caustic Splash Injuries
For caustic splash injuries, immediate irrigation should be performed first, without delay, using running water for at least 15 minutes. 1, 2
Initial Management Algorithm
Immediate Irrigation
Dry Chemical Considerations
During Irrigation
Evidence and Rationale
The 2024 American Heart Association guidelines strongly recommend immediate skin decontamination after chemical exposure (Class 1, Level B-NR) 1. Observational studies have shown that patients who received immediate irrigation within 10 minutes with a large volume of water for at least 15 minutes had:
- Decreased degree of full-thickness burns
- Reduced number of full-thickness burns
- Shorter mean hospital stays 1
A study of 83 patients demonstrated that those who received copious water irrigation within 3 minutes of exposure had:
- Lower likelihood of progression to full-thickness burns (13.5% vs 60.8%)
- Fewer delayed complications (5.4% vs 30.4%)
- Shorter hospital stays (6.2 vs 22 days) 3
Special Considerations
Chemical-Specific Protocols: Some chemicals require specific decontamination approaches:
Eye Injuries: For chemical splashes to the eyes:
When to Seek Advanced Care: Call emergency medical services when:
- Patient has respiratory symptoms
- Patient has systemic symptoms
- Exposure involves large areas 1
Common Pitfalls to Avoid
- Delaying irrigation to find "ideal" solutions can significantly worsen outcomes 2
- Insufficient irrigation duration - the full 15 minutes is necessary regardless of symptom improvement 2
- Failing to remove contaminated clothing which can trap chemicals against skin 1
- Attempting to neutralize acids with bases can generate heat and worsen injury 2
- Using high-pressure water streams can cause additional trauma, especially for eye injuries 2
Remember that rapid removal of the caustic agent is the key to first aid, and running water is a readily available and effective decontamination agent for most chemical exposures 1, 3.