Dosage of Augmentin (Amoxicillin/Clavulanic Acid) for a 12.2 kg Child
For a 12.2 kg female child, the appropriate dose of Augmentin is 25 mg/kg/day of the amoxicillin component divided into 2 doses, which equals approximately 305 mg per day or 152.5 mg twice daily. 1
Dosing Calculation
The dosing of Augmentin (amoxicillin/clavulanic acid) for pediatric patients is based on the amoxicillin component and the child's weight. According to clinical guidelines:
- For mild to moderate infections: 25 mg/kg/day of amoxicillin component divided into 2 doses 1
- For severe infections: 45 mg/kg/day of amoxicillin component divided into 2 doses 1
For this 12.2 kg child:
- Standard dose (mild/moderate infection): 12.2 kg × 25 mg/kg/day = 305 mg/day
- Divided into twice daily dosing: 152.5 mg twice daily
Formulation Selection
Augmentin is available in several formulations:
- Oral suspension (commonly 125 mg/5 mL, 200 mg/5 mL, or 400 mg/5 mL)
- Chewable tablets (various strengths)
For a 12.2 kg child, the oral suspension is typically the most appropriate formulation. The exact volume to administer will depend on the concentration of the suspension.
Administration Guidelines
- Administer at the start of a meal to minimize gastrointestinal intolerance 2
- Complete the full course of treatment (typically 7-10 days)
- For infections caused by Streptococcus pyogenes, treatment should continue for at least 10 days to prevent acute rheumatic fever 2
Special Considerations
- If treating a more severe infection (such as severe skin/skin structure infections or lower respiratory tract infections), the higher dose of 45 mg/kg/day (approximately 275 mg twice daily for this child) may be warranted 1
- For recurrent or persistent infections where resistant pathogens are suspected, the higher dose formulation may be considered 3
- Monitor for common side effects, which include mild gastrointestinal disturbances, particularly diarrhea 3
Important Caveats
- Twice-daily dosing is associated with better compliance and fewer gastrointestinal side effects than three-times-daily dosing 3
- If the child has renal impairment, dose adjustment may be necessary 2
- Always shake oral suspension well before using 2
- Any unused portion of reconstituted suspension must be discarded after 14 days 2
This dosing recommendation aligns with established guidelines for pediatric antibiotic therapy and provides appropriate coverage for common pediatric infections while minimizing the risk of side effects.