From the Research
Prevalence of Tardive Dysphoria in Patients Taking SSRIs
- The prevalence of tardive dysphoria in patients taking Selective Serotonin Reuptake Inhibitors (SSRIs) is not directly stated in the provided studies, but there is evidence of SSRIs being associated with tardive syndrome 1, 2.
- A retrospective epidemiological study found that 14.0% of subjects receiving antidepressants, including SSRIs, for over 6 months developed at least one tardive syndrome, with tardive dystonia being the most common subtype 2.
- Another study presented a series of five cases of tardive dysphoria, all of which manifested after prolonged use of SSRIs, suggesting a possible link between SSRIs and tardive dysphoria 1.
- However, the exact prevalence of tardive dysphoria in patients taking SSRIs is not specified in the provided studies.
Associated Factors and Side Effects
- The use of serotonin-norepinephrine reuptake inhibitors and previous marital status were found to significantly increase the risk of tardive syndrome in patients taking antidepressants, including SSRIs 2.
- Common side effects of SSRIs reported in a naturalistic setting include flatulence, somnolence, memory impairment, decreased concentration, yawning, fatigue, dry mouth, weight gain, light headedness, and sweating 3.
- Different SSRIs, such as sertraline, escitalopram, and fluoxetine, may have distinct side effect profiles, with escitalopram being associated with a higher incidence of headache, pruritus, memory impairment, decreased concentration, and dizziness 3.