Workup and Treatment Plan for Acute Low Back Pain
For acute low back pain, the recommended approach is to start with conservative therapies including local heat application, maintaining tolerable physical activity, and using acetaminophen or NSAIDs for pain management, while avoiding imaging unless red flags are present. 1
Diagnostic Workup
Initial Assessment
- Document presence of red flags that require urgent intervention:
- Fever, night pain, constant pain unrelieved by position change
- Bowel/bladder dysfunction, saddle anesthesia
- Progressive neurological deficits
- Recent trauma (especially in elderly or osteoporotic patients)
- History of immunosuppression (HIV, chronic steroids, transplant medications)
- Unexplained weight loss or cancer history 1
Imaging
- Avoid routine imaging for acute low back pain without red flags
- If red flags are present, MRI of the lumbar spine without IV contrast is the preferred initial imaging modality
- Consider upright radiographs with flexion/extension views only if instability is suspected 1
Treatment Algorithm
First-Line Interventions (0-2 weeks)
Non-pharmacological approaches:
Pharmacological management:
- Acetaminophen (up to 3000mg/day) as first option due to safety profile
- NSAIDs (ibuprofen, naproxen) if acetaminophen is insufficient
- Use with caution in elderly patients or those with renal/hepatic impairment
- Short-term muscle relaxants (e.g., cyclobenzaprine) for 2-3 weeks maximum
Second-Line Interventions (2-4 weeks if no improvement)
Physical treatments:
Adjunctive approaches:
- Mind-body approaches (mindfulness-based stress reduction, tai chi, yoga)
- Cognitive-behavioral therapy to address fear of movement 1
For Persistent Pain (4-6 weeks)
- Reassess for missed serious pathology
- Consider gabapentin or pregabalin if neuropathic pain component is present
- Multidisciplinary rehabilitation program combining exercise, physical therapy, and cognitive-behavioral therapy 1
Special Considerations
Medication Cautions
- Avoid opioids as first-line treatment due to risks outweighing benefits
- For cyclobenzaprine:
- Titrate slowly in elderly patients and those with hepatic impairment
- Start with 5mg dose in these populations
- Combination with NSAIDs may increase drowsiness 3
When to Refer
- Surgical consultation only for:
Prognosis and Follow-up
- 90% of acute low back pain cases follow a benign course with resolution
- Recurrence is common; educate patients on prevention strategies
- Reassess treatment plan if patient does not return to normal activity within 4-6 weeks 2, 4