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Last updated: August 18, 2025View editorial policy

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Differential Diagnosis for Heel Pain

  • Single Most Likely Diagnosis
    • Plantar fasciitis: This is the most common cause of heel pain, resulting from inflammation of the plantar fascia, a band of tissue that runs along the bottom of the foot. It is often associated with overuse, poor foot mechanics, or inadequate footwear.
  • Other Likely Diagnoses
    • Achilles tendinitis: Inflammation of the Achilles tendon, which connects the calf muscles to the heel bone, can cause heel pain, especially with activities that involve running or jumping.
    • Heel spur: A bony growth on the underside of the heel bone, which can cause pain when walking or standing.
    • Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion the joints and reduce friction between bone and soft tissue can lead to heel pain.
    • Fat pad atrophy: Thinning of the fat pad under the heel can cause pain, especially in older adults.
  • Do Not Miss Diagnoses
    • Calcaneal fracture: A break in the heel bone, which can be caused by a fall from a height or a sudden impact. Missing this diagnosis could lead to improper healing and chronic pain.
    • Osteomyelitis: A bone infection that can cause severe pain and requires prompt antibiotic treatment to prevent serious complications.
    • Tumor: Although rare, tumors such as osteoid osteoma or Ewing's sarcoma can cause heel pain and must be considered to ensure timely diagnosis and treatment.
  • Rare Diagnoses
    • Rheumatoid arthritis: An autoimmune disorder that can cause inflammation and pain in the heel, among other joints.
    • Gout: A form of arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness, which can occur in the heel.
    • Paget's disease: A condition that affects bone remodeling, leading to weakened bones and potential pain, including in the heel.
    • Entrapment of the posterior tibial nerve or the first branch of the lateral plantar nerve: Compression of these nerves can cause heel pain and must be considered in the differential diagnosis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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