MRI for Discitis: Optimal Protocol and Technique
MRI without and with IV contrast is the gold standard imaging modality for diagnosing discitis, with a sensitivity of 96%, specificity of 94%, and accuracy of 92%. 1
Optimal MRI Protocol for Discitis
Essential Sequences
- T1-weighted sagittal and axial images
- T2-weighted sagittal and axial images with fat suppression (STIR or T2 fat-sat)
- Post-contrast T1-weighted sagittal and axial images with fat suppression
The examination should include:
- Complete coverage of the affected spinal region
- Fat suppression techniques for both pre- and post-contrast imaging
- Diffusion-weighted imaging (DWI) sequences
Key Technical Considerations
- Fat suppression is critical - STIR or T2 fat-sat sequences are necessary to identify marrow edema, paraspinal inflammation, and soft tissue abnormalities 1
- Both pre- and post-contrast imaging - Pre-contrast images are required for comparison to accurately assess enhancement patterns 1
- Contrast enhancement - IV contrast increases lesion conspicuity and helps define the extent of infection 1
- Diffusion-weighted imaging - Helps differentiate infectious spondylitis from degenerative (Modic type 1) changes 1
Diagnostic Value and Findings
Primary MRI Findings in Discitis
- Vertebral endplate erosions with adjacent marrow edema
- Disc space narrowing with abnormal signal intensity
- Paraspinal and epidural soft tissue inflammation/abscess
- Enhancement of affected vertebrae, disc space, and adjacent soft tissues
Specific Diagnostic Signs
- The superior-inferior paraspinal edema ratio (SI-PER) ≥2.5 has 96% sensitivity and 75% specificity for discitis 2
- Epidural enhancement on contrast-enhanced MRI combined with abnormal lab values predicts positive biopsy results for spondylodiscitis 1
Alternative Imaging When MRI Contraindicated
If MRI cannot be performed (e.g., implantable devices, claustrophobia):
- Combination spine gallium/Tc99 bone scan - Second-line option 1
- CT with contrast - Less sensitive but useful for bony detail and guiding biopsy 1
- PET/CT - May be used as a complementary examination in select cases 1
Common Pitfalls to Avoid
- Inadequate sequences - Standard protocols for disc disease without fat suppression are insufficient for detecting inflammatory changes 3
- MRI with contrast only - Pre-contrast images are essential for comparison 1
- Early imaging limitations - Very early MRI may show atypical findings with involvement limited to the disc, anterior soft tissues, or epidural space rather than the vertebral body 4
- Mimics - Degenerative endplate changes can mimic discitis; diffusion-weighted imaging helps differentiate 1
Follow-up Imaging Considerations
- MRI findings often lag behind clinical improvement 1
- Resolution of subcutaneous fluid collections or decreased signal abnormality in paraspinal or epidural locations suggests treatment response 1
- Consider repeat MRI if initial imaging is negative but clinical suspicion remains high 4
For suspected discitis, radiographs are of limited value in early disease as changes may take 2-8 weeks to appear, and should not delay MRI when clinical suspicion is high 1.