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Differential Diagnosis for Eye Pain with Decreased Visual Acuity

Single Most Likely Diagnosis

  • Acute Angle-Closure Glaucoma: This condition is characterized by sudden onset of eye pain, decreased visual acuity, and often accompanied by nausea, vomiting, and seeing halos around lights. It is a medical emergency requiring immediate treatment to prevent permanent vision loss.

Other Likely Diagnoses

  • Conjunctivitis: Inflammation of the conjunctiva can cause eye pain and decreased visual acuity, especially if there is a significant amount of discharge or if the condition progresses to involve the cornea.
  • Keratitis: Inflammation of the cornea can cause pain, blurred vision, and sensitivity to light. It can be due to infection, injury, or underlying conditions like dry eye.
  • Uveitis: Inflammation of the uvea, which includes the iris, ciliary body, and choroid, can cause eye pain, sensitivity to light, and decreased visual acuity.
  • Retinal Detachment: Although often painless, some patients may experience eye pain along with flashes of light and floaters, leading to decreased visual acuity.

Do Not Miss Diagnoses

  • Endophthalmitis: A severe infection within the eye that can follow surgery, trauma, or blood-borne infection. It presents with severe eye pain, decreased vision, and significant inflammation.
  • Orbital Cellulitis: An infection of the tissues surrounding the eye, which can cause pain, swelling, and decreased visual acuity. It can lead to serious complications if not promptly treated.
  • Temporal Arteritis (Giant Cell Arteritis): An inflammation of the blood vessels that can cause eye pain, headache, and sudden loss of vision in one or both eyes. It is a medical emergency requiring immediate steroid treatment.

Rare Diagnoses

  • Scleritis: A severe inflammation of the sclera that can cause deep, boring eye pain and tenderness, often accompanied by redness and decreased visual acuity.
  • Optic Neuritis: Inflammation of the optic nerve that can cause pain with eye movement, decreased visual acuity, and loss of color vision. It is often associated with multiple sclerosis.
  • Sympathetic Ophthalmia: A rare, inflammatory condition that can occur after penetrating eye injury or surgery, leading to inflammation in the uninjured eye and potentially causing vision loss.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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