Treatment of Travel Diarrhea in Children
The primary treatment for travel diarrhea in children is oral rehydration therapy (ORT) with appropriate oral rehydration solution (ORS), early refeeding, and selective use of medications based on severity. 1, 2
Assessment and Classification
First, determine the severity of diarrhea:
- Mild: Tolerable, not distressing, doesn't interfere with activities
- Moderate: Distressing or interferes with planned activities
- Severe: Incapacitating or completely prevents planned activities; all dysentery (bloody stools) is considered severe 1
Treatment Algorithm
1. Rehydration (First Priority)
Mild to moderate dehydration: Use oral rehydration solution (ORS)
Severe dehydration: Start with intravenous fluids (60-100 mL/kg of 0.9% saline) to restore circulation, then transition to ORS 2, 4
2. Nutritional Management
- Continue breastfeeding throughout the diarrheal episode 2
- Resume age-appropriate diet during or immediately after rehydration 2
- Avoid food restriction as early refeeding decreases intestinal permeability and improves outcomes 2
- Recommended foods: Small light meals, starches, cereals, yogurt, fruits, vegetables 2
- Avoid: Fatty foods, heavy/spicy foods, caffeine, and lactose-containing foods 2
3. Medication Management
For Mild Diarrhea:
- No antibiotics recommended 1
- Bismuth subsalicylate may be considered for children over 3 years (age-appropriate dosing) 1
- Avoid loperamide in children under 18 years 2
For Moderate Diarrhea:
- Antibiotics generally not needed unless symptoms persist 1
- If vomiting is present, ondansetron (4 mg single dose, can be repeated if needed) may facilitate oral rehydration 2
For Severe Diarrhea:
- Antibiotics recommended 1
- Azithromycin is preferred for severe travelers' diarrhea in children 1
- Avoid fluoroquinolones in children due to potential adverse effects 1, 2
Warning Signs Requiring Medical Attention
- Bloody diarrhea
- Persistent vomiting
- Signs of severe dehydration (severe lethargy, altered consciousness)
- High fever
- No improvement within 48 hours 2
Prevention Strategies
- Hand hygiene: Thorough handwashing after using toilet, before and after preparing food 2
- Safe food and water practices: Avoid untreated water, unpeeled fruits/vegetables, undercooked foods
- Bismuth subsalicylate may be considered for prevention in children over 3 years 1
- Avoid routine antimicrobial prophylaxis in children 1
Common Pitfalls to Avoid
- Delaying rehydration: Start ORT immediately when diarrhea begins
- Using inappropriate fluids: Sports drinks, juices, and sodas have improper electrolyte compositions and can worsen dehydration 2
- Withholding food: Early refeeding improves outcomes 1, 2
- Overuse of antibiotics: Reserve for severe cases only 1, 2
- Using antidiarrheal medications: Loperamide and other antimotility agents are contraindicated in children under 18 years 2
By following this evidence-based approach focusing on rehydration, appropriate nutrition, and selective medication use, most cases of travel diarrhea in children can be managed effectively while minimizing complications.