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Differential Diagnosis for Atraumatic Swollen Wrist

Single Most Likely Diagnosis

  • Osteoarthritis: This is a common condition that can cause swelling and pain in the wrist, especially in older adults, due to wear and tear of the joint cartilage.

Other Likely Diagnoses

  • Rheumatoid Arthritis: An autoimmune disorder that can cause inflammation and swelling in the wrists and other joints, often presenting with morning stiffness and symmetric joint involvement.
  • Gout: A form of arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness in one or more joints, most often the wrist or big toe.
  • Psoriatic Arthritis: A condition that combines the swollen, scaly skin of psoriasis with joint pain and arthritis, which can cause swelling in the wrist.

Do Not Miss Diagnoses

  • Septic Arthritis: A serious infection within a joint that can cause rapid swelling, pain, and warmth, requiring prompt antibiotic treatment to prevent joint destruction.
  • Ganglion Cyst: A lump or mass that can occur on the wrist, which may cause swelling and can sometimes be painful, but is usually benign.
  • Lymphoma or Other Malignancies: Although rare, certain types of cancer can cause swelling in the wrist due to tumor growth or metastasis.

Rare Diagnoses

  • Hemochromatosis: A genetic disorder characterized by excessive iron accumulation in the body, which can lead to arthritis and swelling in various joints, including the wrist.
  • Sarcoidosis: A condition in which inflammatory cells form lumps known as granulomas in various parts of the body, including the joints, which can cause swelling and pain.
  • Amyloidosis: A group of diseases in which abnormal proteins (amyloid) accumulate in organs and tissues, potentially causing joint swelling among other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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