From the Guidelines
The chance of recurrence of a 10mm hyperplastic polyp in the stomach after removal is relatively low, with an estimated recurrence rate of less than 10%. After complete removal of a gastric hyperplastic polyp, most patients do not experience regrowth at the same site 1. However, it is essential to follow the gastroenterologist's recommendation for surveillance endoscopy, which typically involves a follow-up endoscopy in 1-3 years depending on specific risk factors.
Key Factors to Consider
- Chronic use of proton pump inhibitors (PPIs) may increase recurrence risk
- Persistent H. pylori infection can also increase recurrence risk
- Certain genetic conditions may contribute to a higher recurrence risk
- Hyperplastic polyps are generally benign with very low malignant potential, especially when completely removed
Recommendations for Management
- Follow the gastroenterologist's recommendation for surveillance endoscopy
- Consider reducing or discontinuing PPIs if possible
- Maintain a healthy lifestyle with proper diet and avoid smoking to reduce recurrence risk
- Note that the provided evidence primarily focuses on colorectal polyps, but the general principles of polyp recurrence and management can be applied to gastric hyperplastic polyps, with the understanding that specific guidelines for gastric polyps may differ 1.
From the Research
Recurrence of Hyperplastic Polyps
- The provided studies do not directly address the recurrence of a 10mm hyperplastic polyp in the stomach after removal.
- However, study 2 mentions that gastric polyps are mainly hyperplastic and benign, and endoscopic resection is recommended even though the rate of malignant transformation is very low.
- Study 3 reports that two patients with hypergastrinemia developed hyperplastic polyps, but it does not provide information on the recurrence of hyperplastic polyps after removal.
Risk of Recurrence
- Study 4 discusses the risk of recurrence of high-risk polyps in the colon, but it does not provide information on the stomach.
- Study 5 examines the association between findings from first endoscopy and CRC risk, but it does not address the recurrence of hyperplastic polyps in the stomach.
- Study 6 reports on a new endoscopic mucosal ablation technique to assist complete resection of recurrent, fibrotic colon polyps, but it does not provide information on the stomach.
Gastric Polyp Removal
- Study 2 reports a safe endoscopic resection of a giant gastric polyp using a combination of injection, elevation, endoloop, and argon plasma coagulation (APC).
- However, it does not provide information on the recurrence of hyperplastic polyps after removal.
- Study 3 analyzes the long-term effectiveness of APC for the treatment of gastric antral vascular ectasia (GAVE) and its side effects, but it does not address the recurrence of hyperplastic polyps.