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Last updated: August 19, 2025View editorial policy

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Differential Diagnosis for Cat Scratch

  • Single most likely diagnosis
    • Cat scratch disease (Bartonellosis): This is the most likely diagnosis due to the direct exposure to a cat scratch, which is a common mode of transmission for Bartonella henselae, the bacterium responsible for cat scratch disease.
  • Other Likely diagnoses
    • Cellulitis: A bacterial infection of the skin and subcutaneous tissues, which can occur after a cat scratch, especially if the scratch becomes contaminated with bacteria.
    • Abscess: A localized collection of pus that can form as a result of a bacterial infection, potentially caused by bacteria introduced through the cat scratch.
    • Folliculitis: An inflammation of the hair follicles, which can be caused by bacterial infection, including those introduced by a cat scratch.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Rabies: Although rare, if the cat is infected with rabies, a scratch could potentially transmit the virus, making prompt recognition and treatment critical.
    • Tetanus: A bacterial infection caused by Clostridium tetani, which can enter the body through wounds, including deep scratches, and can be life-threatening if not treated.
  • Rare diagnoses
    • Pasteurella multocida infection: A bacterium commonly found in the mouths of cats and dogs, which can cause infections in humans through bites or scratches, though it's less commonly associated with scratches than bites.
    • Capnocytophaga canimorsus infection: A bacterium found in the mouths of dogs and cats, which can cause severe infections in humans, particularly those who are immunocompromised, though it's more commonly associated with dog bites.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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