Initial Management of Acute Bronchitis
For immunocompetent adult outpatients with acute bronchitis, no routine medications should be prescribed, as these treatments have not been shown to be safe and effective at making cough less severe or resolve sooner. 1
Diagnostic Approach
Acute bronchitis is a clinical diagnosis characterized by:
- Acute cough (typically lasting 2-3 weeks)
- Inflammation of the tracheobronchial tree
- Absence of pneumonia, asthma, or COPD exacerbation
Key Clinical Assessment:
- Evaluate for risk factors for severe disease
- Assess respiratory status (rate, work of breathing)
- Rule out serious differential diagnoses:
- Pneumonia
- Asthma exacerbation
- COPD exacerbation
- Heart failure
Diagnostic Testing:
- No routine investigations are recommended for initial presentation 1
- Do not routinely order:
- Chest x-ray
- Spirometry
- Peak flow measurement
- Sputum cultures
- Viral PCR
- Serum inflammatory markers (CRP, procalcitonin)
Management Algorithm
1. Initial Presentation:
- Supportive care only 1, 2
- Patient education about expected course (cough typically lasts 2-3 weeks)
- Reassurance about self-limiting nature of the condition
2. Supportive Measures:
- Adequate hydration
- Rest
- Avoidance of respiratory irritants (tobacco smoke)
3. Medication Recommendations:
- Avoid routine prescription of: 1
- Antibiotics
- Antiviral therapy
- Antitussives
- Inhaled beta agonists
- Inhaled anticholinergics
- Inhaled or oral corticosteroids
- Oral NSAIDs
4. Follow-up Recommendations:
- Advise patient to return if symptoms:
- Persist beyond 3 weeks
- Worsen significantly
- Include new concerning features (high fever, shortness of breath, chest pain)
5. For Worsening Symptoms:
Reassess for complications or alternative diagnoses
Consider targeted investigations: 1
- Chest x-ray
- Sputum culture
- Complete blood count
- Inflammatory markers
Consider antibiotics only if: 1, 3
- Complicating bacterial infection is likely
- Patient has risk factors (age ≥65, comorbidities)
- Symptoms include increased dyspnea, sputum production, and purulence
Evidence Analysis
The American College of Chest Physicians (2020) guidelines strongly recommend against routine medications for acute bronchitis, emphasizing that acute bronchitis is predominantly viral (>90% of cases) and self-limiting 1, 2. This recommendation is supported by evidence showing that antibiotics provide minimal benefit (reducing cough duration by only about 0.5 days) while exposing patients to adverse effects 2.
The evidence for other treatments is similarly lacking. Studies have not demonstrated meaningful clinical benefit from antitussives, bronchodilators, or corticosteroids in patients without underlying pulmonary disease 1, 4, 2.
Common Pitfalls to Avoid
Unnecessary antibiotic prescribing: Despite clear evidence against their routine use, antibiotics are frequently prescribed for acute bronchitis. This contributes to antibiotic resistance without improving patient outcomes 1, 4, 2.
Misdiagnosis: Failing to distinguish acute bronchitis from conditions requiring specific treatment (pneumonia, asthma, COPD exacerbation) 4.
Overreliance on sputum color: The presence of colored (e.g., green) sputum does not reliably differentiate between bacterial and viral infections 4.
Inadequate patient education: Not informing patients about the expected duration of symptoms (typically 2-3 weeks) can lead to unnecessary follow-up visits and pressure for antibiotic prescriptions 2.
Missing underlying conditions: In patients with recurrent episodes of "acute bronchitis," consider underlying conditions such as asthma (found in up to 65% of patients with recurrent episodes) 1.
By following these evidence-based recommendations, clinicians can provide appropriate care for patients with acute bronchitis while avoiding unnecessary treatments and reducing antibiotic overuse.