Treatment for Poison Ivy
As soon as exposure to poison ivy is recognized, the affected area should be washed immediately with soap and water or a commercial decontamination product to remove the urushiol oil. 1, 2
Immediate Management
Decontamination:
- Wash exposed area with soap and water or commercial decontamination product
- Effectiveness decreases rapidly with time: 100% effective immediately, 50% at 10 minutes, 25% at 15 minutes, 10% at 30 minutes 1
- Also wash clothing, tools, and pets that may have contacted the plant
Symptomatic Relief Measures:
Medication Options
Topical Treatments:
- High-potency topical corticosteroids (e.g., clobetasol propionate 0.05%) applied twice daily for moderate cases 2
- Avoid low-potency OTC hydrocortisone (0.2-2.5%) as these have limited efficacy for poison ivy dermatitis 1, 2
- For facial/eyelid involvement: Tacrolimus 0.1% ointment is preferred over corticosteroids to avoid skin atrophy 2
Oral Medications:
- Antihistamines: Limited evidence for effectiveness against poison ivy itch, but may help with sleep disturbance 1, 2
Treatment Based on Severity
Mild Cases:
- Cool compresses
- Oatmeal baths
- High-potency topical corticosteroids
Moderate Cases:
- All treatments for mild cases
- Consider short course of systemic corticosteroids if widespread
Severe Cases (extensive blistering, facial/genital involvement, or systemic symptoms):
- Seek medical attention
- May require systemic corticosteroids
- Monitor for secondary infection
Important Considerations
Avoid common pitfalls:
When to seek medical attention:
- Severe or widespread rash
- Facial, genital, or widespread involvement
- Signs of infection (increased pain, swelling, warmth, pus)
- History of severe reactions to poison ivy
- Symptoms not improving after 7-10 days of self-treatment
The rash typically resolves within 1-3 weeks without treatment 3, 4, but appropriate interventions can significantly reduce discomfort and potentially shorten the duration of symptoms.