What are the clinical indications and generic alternatives for Vezah (Perphenazine)?

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Last updated: March 9, 2025 • View editorial policy

From the Research

Perphenazine, also known by the brand name Vezah, is typically used for the treatment of schizophrenia and other psychoses, and there are generic alternatives available, including other typical antipsychotics such as haloperidol or chlorpromazine. The clinical indications for Perphenazine include the management of schizophrenia, acute psychosis, and severe behavioral disorders.

  • The standard dosage of Perphenazine varies depending on the condition being treated, but it is usually started at a low dose and gradually increased as needed and tolerated.
  • Generic alternatives to Perphenazine include other typical antipsychotics, such as haloperidol or chlorpromazine, which may be considered for patients who cannot take Perphenazine due to contraindications, cost concerns, or personal preference.
  • It is essential to note that the provided evidence 1, 2, 3, 4, 5 does not directly address the question about Perphenazine, as it primarily discusses the treatment of hypertension with various medications, including amlodipine, lisinopril, and chlorthalidone.
  • However, based on general medical knowledge, Perphenazine is a typical antipsychotic medication that can be used to treat various psychiatric conditions, and its use should be guided by the clinical judgment of a healthcare professional, taking into account the patient's specific needs and medical history.
  • In terms of morbidity, mortality, and quality of life, the treatment of schizophrenia and other psychoses with Perphenazine or other antipsychotic medications can significantly improve symptoms and functioning, but it is crucial to carefully weigh the potential benefits and risks, including the risk of side effects such as extrapyramidal symptoms, tardive dyskinesia, and increased mortality in elderly patients with dementia-related psychosis 1.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.