What is the most likely injury when an ankle inverts?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Ankle Injury with Inward Roll

When someone's ankle rolls inward or medially, several injuries can occur. Here's a differential diagnosis organized into categories:

  • Single most likely diagnosis
    • Ankle sprain: This is the most common injury when the ankle rolls inward. The medial ligaments, particularly the deltoid ligament, are stretched or torn, leading to pain, swelling, and instability.
  • Other Likely diagnoses
    • Medial ankle fracture: A fracture of the medial malleolus or other bones in the medial ankle can occur, especially if the force of the roll is significant.
    • Peroneal tendon injury: The peroneal tendons, which run along the lateral ankle, can be stretched or torn when the ankle rolls inward, causing pain and weakness.
    • Syndesmotic injury: The syndesmosis, a ligamentous complex between the tibia and fibula, can be injured when the ankle rolls inward, leading to pain and instability.
  • Do Not Miss diagnoses
    • Compartment syndrome: Although rare, compartment syndrome is a potentially devastating condition that can occur after an ankle injury. Increased pressure within the muscle compartments can lead to nerve and muscle damage, making prompt diagnosis and treatment crucial.
    • Fracture with dislocation: A fracture with dislocation of the ankle joint can occur, which requires prompt reduction and stabilization to prevent long-term damage.
  • Rare diagnoses
    • Osteochondral lesion: An osteochondral lesion, where a piece of cartilage and bone is damaged, can occur in the ankle joint, especially with a severe roll.
    • Nerve injury: Injury to the nerves surrounding the ankle, such as the peroneal or tibial nerves, can occur, although this is relatively rare.
    • Vascular injury: Injury to the blood vessels surrounding the ankle, such as the posterior tibial artery, can occur, although this is rare and usually associated with more severe trauma.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.