What is Adagen (Pegademase)?

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Last updated: March 9, 2025View editorial policy

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From the Research

Adagen (Pegademase) is an enzyme replacement therapy used to treat severe combined immunodeficiency disease (SCID) associated with adenosine deaminase (ADA) deficiency, which is a rare genetic disorder that affects the immune system. Unfortunately, none of the provided studies directly address Adagen (Pegademase) or its use in treating SCID associated with ADA deficiency. However, based on general medical knowledge,

  • Adagen (Pegademase) works by replacing the deficient ADA enzyme, which helps to break down toxic substances that can accumulate in the body and damage the immune system.
  • The typical dosage of Adagen (Pegademase) is administered via intramuscular injection, and the frequency of administration may vary depending on the individual patient's needs.
  • Patients receiving Adagen (Pegademase) should be monitored regularly for potential side effects, such as injection site reactions, and for signs of immune system improvement.
  • Adagen (Pegademase) has been shown to improve immune function and reduce the risk of infections in patients with SCID associated with ADA deficiency, as reported in various studies, although not cited here 1, 2, 3, 4, 5. It is essential to note that the provided studies do not directly address Adagen (Pegademase) or its use in treating SCID associated with ADA deficiency. Therefore, the information provided is based on general medical knowledge and may not be supported by the specific studies cited.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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