What are the directions for using ketoconazole (antifungal medication) 2% shampoo for treating fungal infections or seborrheic dermatitis of the scalp?

Ketoconazole 2% Shampoo Directions for Use

For treating fungal infections or seborrheic dermatitis of the scalp, ketoconazole 2% shampoo should be applied twice weekly for 2-4 weeks during the initial treatment phase, followed by once-weekly application for maintenance to prevent recurrence. 1, 2

Initial Treatment Protocol

Application Method:

• Wet hair and scalp thoroughly with water
• Apply enough shampoo to create a lather
• Massage into the scalp for 1-2 minutes
• Leave on the scalp for an additional 3-5 minutes
• Rinse thoroughly with water
• Repeat if directed on the product label

Treatment Schedule:

• Seborrheic Dermatitis/Dandruff:

  • Apply twice weekly for 2-4 weeks 1
  • Space applications evenly throughout the week (e.g., Monday and Thursday)
  • Continue until clinical improvement is seen

• Fungal Infections:

  • Apply twice weekly for at least 2-4 weeks 3
  • May require longer treatment depending on severity and type of infection

Maintenance Therapy

After successful initial treatment:

• Reduce to once-weekly application to prevent relapse 1
• Continue maintenance therapy for several months as needed
• For severe cases, consider alternating with other medicated shampoos as directed by your healthcare provider 4

Efficacy and Expectations

• Approximately 88% of patients show excellent response after 2-4 weeks of twice-weekly use 1
• Clinical improvement should be noticeable within the first 2 weeks of treatment
• Significant reduction in scaling, erythema, and pruritus can be expected 5
• The medication works by targeting Pityrosporum ovale (Malassezia), which plays an important role in seborrheic dermatitis 1, 6

Important Considerations

• Do not use more often than prescribed, as this will not improve results and may cause irritation
• Complete the full course of treatment even if symptoms improve quickly
• Keep the scalp dry between applications
• Avoid getting shampoo in eyes; if contact occurs, rinse thoroughly with water
• For best results, do not use other medicated shampoos during treatment unless specifically directed by your healthcare provider

When to Seek Medical Advice

• If no improvement after 2-4 weeks of treatment
• If condition worsens during treatment
• If severe irritation, redness, or burning occurs
• If symptoms return quickly after completing treatment

Ketoconazole 2% shampoo is well-tolerated with minimal side effects and provides both effective treatment and prevention of scalp fungal infections and seborrheic dermatitis when used as directed 1, 7.