What are the effects of injecting a deep pimple (acne cyst)?

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Last updated: March 10, 2025View editorial policy

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From the Guidelines

I strongly advise against injecting deep pimples at home, as this can lead to serious complications and scarring, and instead recommend consulting a dermatologist for proper treatment, such as intralesional corticosteroid injections, which can help reduce inflammation and speed healing 1.

Effects of Injecting a Deep Pimple

Injecting a deep pimple, also known as a cystic acne lesion, can have significant effects on the skin and overall health. The most effective and safe way to manage deep pimples is under the care of a dermatologist.

Recommended Treatment

  • Intralesional corticosteroid injections: These are recommended as an adjuvant therapy for larger acne lesions to reduce inflammation and speed healing 1.
  • Topical treatments: Use topical treatments containing benzoyl peroxide (2.5-10%) or salicylic acid (0.5-2%) to help manage deep pimples at home.
  • Warm compresses: Apply warm compresses for 10-15 minutes several times daily to reduce inflammation.
  • Avoid squeezing or picking: Refrain from squeezing or picking at deep pimples, as this can worsen inflammation and cause scarring.
  • Over-the-counter pain relievers: Use over-the-counter pain relievers like ibuprofen (400mg every 6-8 hours) to help manage pain and inflammation.

Importance of Professional Treatment

If a deep pimple is particularly painful, large, or doesn't improve within 1-2 weeks with home care, it is essential to see a dermatologist for professional treatment. A dermatologist can assess the lesion and provide appropriate treatment, including intralesional corticosteroid injections, to prevent complications and promote healing.

Key Considerations

  • Intralesional corticosteroid injections should be used judiciously for patients who are at risk of acne scarring and/or for rapid improvement in inflammation and pain 1.
  • Using a lower concentration and volume of corticosteroid can minimize the risks of local corticosteroid adverse events 1.

From the Research

Effects of Injecting a Deep Pimple (Acne Cyst)

  • The provided studies do not directly address the effects of injecting a deep pimple (acne cyst) 2, 3, 4, 5, 6.
  • However, the studies discuss the use of intralesional injections, such as triamcinolone acetonide, for the treatment of keloids and hypertrophic scars, which may be related to acne cysts.
  • Common adverse effects of intralesional corticosteroid injection include localized hypopigmentation, depigmentation, skin atrophy, and lipoatrophy 2, 4, 5.
  • The efficacy and safety of intralesional triamcinolone acetonide for keloids and hypertrophic scars have been evaluated in several studies, with variable results 3, 4, 5.
  • Intralesional triamcinolone acetonide injection has also been used to treat primary and recurrent chalazia, with reported success rates and minimal complications 6.

Adverse Effects

  • Localized hypopigmentation and depigmentation have been reported as adverse effects of intralesional corticosteroid injection 2, 4, 5.
  • Skin atrophy and lipoatrophy are also potential adverse effects of intralesional corticosteroid injection 2, 4, 5.
  • Other reported adverse effects include fever, flu-like symptoms, mild pain, and inflammation at the injection site 3, 5.

Efficacy

  • The efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars has been evaluated in several studies, with variable results 3, 4, 5.
  • Intralesional triamcinolone acetonide injection has been reported to be effective in achieving lesion regression in primary and recurrent chalazia 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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