What are the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) criteria for a chronic Post-Traumatic Stress Disorder (PTSD) diagnosis?

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DSM-5 Criteria for Chronic PTSD Diagnosis

According to the DSM-5, chronic PTSD is diagnosed when symptoms persist for more than 3 months following exposure to a traumatic event, with specific criteria across five domains that must be met for diagnosis.

Criterion A: Stressor

  • Exposure to actual or threatened death, serious injury, or sexual violence through:
    • Direct experience
    • Witnessing the event
    • Learning about traumatic event occurring to a close family member/friend
    • Experiencing repeated or extreme exposure to aversive details of traumatic events

Criterion B: Intrusion Symptoms (≥1 required)

  • Recurrent, involuntary, and intrusive distressing memories
  • Recurrent distressing dreams related to the event
  • Dissociative reactions (flashbacks) where the person feels or acts as if the event were recurring
  • Intense or prolonged psychological distress at exposure to cues
  • Marked physiological reactions to cues that symbolize or resemble the event 1, 2

Criterion C: Avoidance (≥1 required)

  • Persistent avoidance of stimuli associated with the traumatic event:
    • Avoidance of distressing memories, thoughts, or feelings
    • Avoidance of external reminders (people, places, activities, objects, situations) 1, 2

Criterion D: Negative Alterations in Cognitions and Mood (≥2 required)

  • Inability to remember important aspects of the event
  • Persistent negative beliefs about oneself, others, or the world
  • Distorted cognitions about the cause or consequences leading to blame
  • Persistent negative emotional state
  • Markedly diminished interest in significant activities
  • Feelings of detachment or estrangement from others
  • Persistent inability to experience positive emotions 1, 2

Criterion E: Alterations in Arousal and Reactivity (≥2 required)

  • Irritable behavior and angry outbursts
  • Reckless or self-destructive behavior
  • Hypervigilance
  • Exaggerated startle response
  • Problems with concentration
  • Sleep disturbance 1, 2

Duration and Functional Impairment

  • Criterion F: Duration - Symptoms persist for more than 3 months (for chronic specification)
  • Criterion G: Functional Significance - Symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning
  • Criterion H: Exclusion - Disturbance is not attributable to physiological effects of a substance or another medical condition 2

Specifiers

  • With dissociative symptoms: Either depersonalization or derealization
  • With delayed expression: Full criteria not met until at least 6 months after the event 3

Key Diagnostic Changes in DSM-5

  • PTSD was moved from anxiety disorders to a new category called "Trauma and Stressor-related Disorders" 3
  • The subjective reaction criterion (former A2 criterion requiring fear, helplessness, or horror) was eliminated 4, 3
  • The symptom clusters were expanded from three to four, with the addition of "negative alterations in cognitions and mood" as a separate cluster 5, 3
  • The scope of symptoms was expanded beyond fear-based reactions to include dysphoric, anhedonic, aggressive/externalizing, guilt/shame, and dissociative symptoms 5

Common Diagnostic Pitfalls

  • Failing to distinguish between acute PTSD (symptoms lasting 1-3 months) and chronic PTSD (symptoms lasting >3 months)
  • Overlooking avoidance symptoms, which are required but may be subtle
  • Missing the functional impairment criterion, which is essential for diagnosis
  • Not considering cultural factors that may influence symptom presentation 6
  • Confusing Complex PTSD (recognized in ICD-11 but not in DSM-5) with chronic PTSD 1

Differential Diagnosis

  • Adjustment disorder (less severe stressor or different symptom profile)
  • Acute stress disorder (similar symptoms but duration less than 1 month)
  • Other trauma-related disorders (reactive attachment disorder, disinhibited social engagement disorder)
  • Major depressive disorder
  • Anxiety disorders
  • Substance-induced disorders 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Post-Traumatic Stress Disorder (PTSD)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Considering PTSD for DSM-5.

Depression and anxiety, 2011

Research

[Diagnostic Criteria of PTSD in ICD10, ICD-11 and DSM 5: Relevance for expert opinion].

Psychotherapie, Psychosomatik, medizinische Psychologie, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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