From the Research
For vitamin D toxicity with a level of 290 ng/mL, I recommend rechecking vitamin D levels every 2-4 weeks until levels return to normal range (30-80 ng/mL). Immediately discontinue all vitamin D supplements and limit dietary sources of vitamin D. Treatment typically involves stopping the source of excess vitamin D and ensuring adequate hydration. In severe cases with symptoms like nausea, vomiting, weakness, or confusion, medical attention should be sought immediately. The frequent monitoring is necessary because vitamin D has a long half-life (about 2-3 weeks) and is stored in fat tissue, meaning levels decrease slowly 1. Calcium levels should also be monitored as hypercalcemia is a dangerous complication of vitamin D toxicity. Once levels begin to normalize, the frequency of testing can be reduced to monthly until completely normal, then annually for maintenance.
Key Considerations
- The patient's hypercalcemia level of 290 ng/mL is a significant concern and requires immediate attention 2.
- Discontinuing vitamin D supplements and limiting dietary sources is crucial in managing vitamin D toxicity 3.
- Monitoring calcium levels is essential to prevent complications associated with hypercalcemia 4.
- The long half-life of vitamin D and its storage in fat tissue necessitate frequent monitoring to ensure levels decrease slowly 5.
Treatment Approach
- Stop all vitamin D supplements and limit dietary sources of vitamin D.
- Ensure adequate hydration to help reduce calcium levels.
- Monitor vitamin D levels every 2-4 weeks until they return to normal range.
- Monitor calcium levels regularly to prevent complications associated with hypercalcemia.
- Consider medical attention immediately if symptoms like nausea, vomiting, weakness, or confusion occur.