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Last updated: August 22, 2025View editorial policy

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Differential Diagnosis for Malrotation and Midgut Volvulus

Single Most Likely Diagnosis

  • Malrotation with Midgut Volvulus: This is the most likely diagnosis given the clinical presentation, as malrotation can lead to midgut volvulus, which is a surgical emergency. The clinical presentation often includes severe abdominal pain, vomiting, and possible bloody stools, along with laboratory findings that may indicate intestinal obstruction or ischemia.

Other Likely Diagnoses

  • Intussusception: A condition where a part of the intestine telescopes into another, which can cause intestinal obstruction and ischemia, presenting with abdominal pain, vomiting, and bloody stools.
  • Incercerated Hernia: A hernia that becomes trapped and can lead to intestinal obstruction and ischemia, presenting with severe abdominal pain and vomiting.
  • Gastroenteritis: An inflammation of the gastrointestinal tract, usually caused by infection, which can present with abdominal pain, vomiting, and diarrhea, but typically does not cause the severe, acute abdomen seen with malrotation and midgut volvulus.

Do Not Miss Diagnoses

  • Appendicitis: Although the presentation can be different, appendicitis is a surgical emergency that can sometimes mimic the symptoms of malrotation and midgut volvulus, especially if the appendix is located in an unusual position due to malrotation.
  • Mesenteric Thrombosis: A blood clot in one of the major arteries that supply blood to the intestine, which can cause severe abdominal pain and intestinal ischemia, requiring prompt diagnosis and treatment.
  • Meconium Ileus: A condition in newborns where the small intestine is obstructed by meconium, which can be a sign of cystic fibrosis, presenting with abdominal distension and failure to pass meconium.

Rare Diagnoses

  • Chronic Intestinal Pseudo-obstruction: A rare condition characterized by recurrent episodes of intestinal obstruction without any physical blockage, which can present with chronic abdominal pain, vomiting, and constipation.
  • Abdominal Lymphoma: A type of cancer that can cause intestinal obstruction and abdominal pain, though it is less common in the presentation of acute abdomen compared to other diagnoses listed here.
  • Congenital Diaphragmatic Hernia: A birth defect where there is a hole in the diaphragm, which can cause abdominal contents to move into the chest and can present with respiratory distress and abdominal symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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