Differential Diagnosis for Electrician's Hand Blister

Single Most Likely Diagnosis

• Contact Dermatitis or Irritant Contact Dermatitis: This is likely due to the use of gloves while working, possibly causing friction or an allergic reaction to the glove material, leading to blister formation. The progression of the blister after continued work supports this diagnosis.

Other Likely Diagnoses

• Friction Blister: Direct friction from the gloves or tools could cause blisters, especially if the electrician was not accustomed to wearing gloves or was using new equipment.
• Allergic Contact Dermatitis: An allergic reaction to the materials in the gloves (e.g., latex, dyes, or other components) could also lead to blister formation.
• Infection (Bacterial or Fungal): The description of the blister becoming bigger, popping, and then forming another blister with a yellowish appearance could indicate a secondary infection, especially if the blister was exposed to contaminants.

Do Not Miss Diagnoses

• Herpes Simplex Virus Infection: Although less common, a herpetic whitlow (a herpes simplex virus infection of the finger or hand) could present with blisters and should be considered, especially if the electrician has a history of herpes simplex infections.
• Erysipelas or Cellulitis: Bacterial infections of the skin that could start with a blister or minor trauma and spread, potentially leading to serious complications if not treated promptly.

Rare Diagnoses

• Dyshidrotic Eczema (Pompholyx): Characterized by small blisters on the hands or feet, this condition could be considered if the blisters are extremely small and the electrician has a history of eczema.
• Bullous Diseases (e.g., Bullous Pemphigoid, Pemphigus Vulgaris): Autoimmune conditions that cause blistering of the skin, which would be rare but should be considered if other diagnoses are ruled out and the condition persists or worsens.