What to do if a blister ruptures?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of Ruptured Blisters

For a ruptured blister, gently cleanse the area with an antimicrobial solution, leave the blister roof intact to serve as a biological dressing, apply a bland emollient, and cover with a non-adherent dressing if necessary. 1

Immediate Care for Ruptured Blisters

  1. Initial Cleaning and Assessment:

    • Gently cleanse the area with an antimicrobial solution 1
    • Assess the size of the affected area and look for signs of infection (redness, warmth, increasing pain, pus)
  2. Blister Management:

    • Leave the blister roof intact - it serves as a biological dressing that protects the healing skin underneath 1, 2
    • If the blister has already ruptured completely, keep the area clean to prevent infection
  3. Pain Management:

    • Apply cold compresses intermittently for the first 24-48 hours to reduce swelling (place a barrier between the cold container and skin) 1
    • Consider over-the-counter pain relievers like acetaminophen or NSAIDs if needed 1

Wound Care

  1. Dressing Application:

    • Apply a bland emollient such as 50% white soft paraffin and 50% liquid paraffin to support barrier function 1
    • Cover with a non-adherent dressing if necessary to protect the area 1
    • Change dressing daily and monitor for signs of infection
  2. Infection Prevention:

    • Wash the area daily with antibacterial products to decrease colonization 1
    • Avoid using alcohol-containing products on damaged skin as they can cause further irritation 1
    • For extensive areas, antiseptic baths or soaks may help dry lesions and prevent infection 1

Special Considerations

  1. For Friction Blisters (common in athletes and active individuals):

    • These typically heal well with conservative treatment 3
    • Adhesive tape has shown better healing outcomes and satisfaction compared to wide area fixation dressings 4
  2. For Burn Blisters:

    • The fluid in burn blisters contains proteins, cytokines, and other components that may affect healing 2
    • Management follows similar principles but may require specialized care for larger burns
  3. When to Seek Medical Attention:

    • If signs of infection develop (increasing redness, warmth, pain, pus, red streaks)
    • If the blister is large (>30% BSA) or involves mucous membranes 5
    • If multiple blisters appear without obvious cause
    • If blisters recur frequently or don't heal properly

Prevention of Future Blisters

  • Wear properly fitted shoes and appropriate socks (acrylic or polyester-wool combinations have been shown to reduce friction blisters) 6
  • Use lubricants in areas prone to friction
  • For activities that commonly cause blisters, consider preventive taping of vulnerable areas

Common Pitfalls to Avoid

  • Don't remove the blister roof if it's still attached - it provides natural protection 1, 2
  • Don't apply home remedies or substances that may introduce infection 1
  • Don't ignore signs of infection which require prompt medical attention
  • Don't use alcohol-containing products on open blisters as they can delay healing 1

References

Guideline

Mosquito Bite Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Role of Burn Blister Fluid in Wound Healing.

Journal of cutaneous and aesthetic surgery, 2021

Research

A Guide to Blister Management.

The Physician and sportsmedicine, 1995

Research

First-Aid Treatment for Friction Blisters: "Walking Into the Right Direction?".

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2018

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Friction blisters. Pathophysiology, prevention and treatment.

Sports medicine (Auckland, N.Z.), 1995

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.