What is the cause of hypogeusia (reduced taste sensation)?

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From the Guidelines

Hypogeusia is most commonly caused by zinc deficiency, which can be treated with supplementation of 25-50mg daily, as supported by the most recent and highest quality study 1.

Causes of Hypogeusia

The causes of hypogeusia can be varied, including:

  • Viral infections
  • Medication side effects
  • Zinc deficiency
  • Aging
  • Smoking
  • Neurological disorders

Importance of Zinc Deficiency

Zinc deficiency is a significant cause of hypogeusia, and supplementation can help restore taste function. According to the espen micronutrient guideline 1, zinc deficiency can cause impaired taste and smell, and supplementation can help alleviate these symptoms.

Treatment Options

Treatment of hypogeusia depends on identifying and addressing the underlying cause. If medication-related, the doctor may adjust dosages or switch medications. For zinc deficiency, supplementation with 25-50mg daily may help restore taste function. Maintaining good oral hygiene, staying hydrated, and avoiding smoking can also improve symptoms.

Additional Considerations

Using flavor enhancers like herbs, spices, or lemon juice can make food more palatable while taste is diminished. Hypogeusia often resolves once the underlying condition is treated, though recovery time varies. The condition occurs because taste receptors on the tongue or the nerves that transmit taste signals to the brain are damaged or affected, disrupting the normal taste perception process. If hypogeusia persists beyond a few weeks or significantly affects eating habits, it is essential to consult a healthcare provider for proper evaluation and treatment.

From the Research

Causes of Hypogeusia

The causes of hypogeusia, a condition characterized by reduced taste sensation, can be varied and multifaceted. Some of the possible causes include:

  • Systemic conditions such as diabetes mellitus, chronic kidney disease, and respiratory infections 2
  • Nutritional deficiencies, including iron deficiency 3
  • Hyposalivation (xerostomia) 4, 3
  • Oral candidiasis 3
  • Psychiatric distress 3
  • Damage to the gustatory afferent nerves and central pathways, such as a unilateral thalamic infarct 5
  • Aging, which can lead to decreased taste sensitivity 4
  • Certain medications, which can induce dysgeusia or hypogeusia 3, 6

Associated Factors

Several factors can contribute to the development of hypogeusia, including:

  • Decreased salivary flow rate 4, 3
  • Elevated taste thresholds 3
  • Malnutrition and weight loss 4, 5
  • Decreased quality of life 2, 4
  • Swallow deficits and psychological elements of the post-stroke condition 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Clinical and physiological investigations in patients with taste abnormality.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1996

Research

[Etiology, diagnostic and therapeutic management of taste disorders].

Therapeutische Umschau. Revue therapeutique, 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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